Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NPS17_RS08760 Genome accession   NZ_CP101985
Coordinates   1850961..1851653 (-) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1845961..1856653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS08735 (NPS17_08735) - 1846020..1846646 (-) 627 WP_002273094.1 hypothetical protein -
  NPS17_RS08740 (NPS17_08740) der 1846721..1848031 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  NPS17_RS08745 (NPS17_08745) dnaI 1848044..1848943 (-) 900 WP_002273096.1 primosomal protein DnaI -
  NPS17_RS08750 (NPS17_08750) - 1848944..1850113 (-) 1170 WP_002273097.1 DnaD domain protein -
  NPS17_RS08755 (NPS17_08755) nrdR 1850100..1850591 (-) 492 WP_002262120.1 transcriptional regulator NrdR -
  NPS17_RS08760 (NPS17_08760) covR 1850961..1851653 (-) 693 WP_002262121.1 response regulator GcrR Regulator
  NPS17_RS08765 (NPS17_08765) - 1852009..1852545 (-) 537 WP_258968991.1 DUF177 domain-containing protein -
  NPS17_RS08770 (NPS17_08770) - 1852538..1853113 (-) 576 WP_002262123.1 TetR/AcrR family transcriptional regulator -
  NPS17_RS08775 (NPS17_08775) - 1853221..1853928 (+) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  NPS17_RS08780 (NPS17_08780) - 1853930..1856542 (+) 2613 WP_258968992.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=713599 NPS17_RS08760 WP_002262121.1 1850961..1851653(-) (covR) [Streptococcus mutans strain COCC33-14R]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=713599 NPS17_RS08760 WP_002262121.1 1850961..1851653(-) (covR) [Streptococcus mutans strain COCC33-14R]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGATACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422