Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   NPS17_RS06830 Genome accession   NZ_CP101985
Coordinates   1487392..1488744 (-) Length   450 a.a.
NCBI ID   WP_002264821.1    Uniprot ID   A0AAX1K2Z0
Organism   Streptococcus mutans strain COCC33-14R     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1482392..1493744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS06820 (NPS17_06820) rnc 1485790..1486485 (-) 696 WP_002266141.1 ribonuclease III -
  NPS17_RS06825 (NPS17_06825) vicX 1486592..1487395 (-) 804 WP_002262928.1 MBL fold metallo-hydrolase Regulator
  NPS17_RS06830 (NPS17_06830) vicK 1487392..1488744 (-) 1353 WP_002264821.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NPS17_RS06835 (NPS17_06835) vicR 1488737..1489444 (-) 708 WP_002262930.1 response regulator YycF Regulator
  NPS17_RS06840 (NPS17_06840) - 1489797..1490579 (+) 783 WP_002262931.1 amino acid ABC transporter ATP-binding protein -
  NPS17_RS06845 (NPS17_06845) - 1490576..1491388 (+) 813 WP_002262932.1 transporter substrate-binding domain-containing protein -
  NPS17_RS06850 (NPS17_06850) - 1491406..1492110 (+) 705 WP_002262933.1 amino acid ABC transporter permease -
  NPS17_RS06855 (NPS17_06855) - 1492125..1492775 (+) 651 WP_002262934.1 amino acid ABC transporter permease -
  NPS17_RS06860 (NPS17_06860) endA 1492843..1493724 (-) 882 WP_258968845.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51752.41 Da        Isoelectric Point: 4.4951

>NTDB_id=713583 NPS17_RS06830 WP_002264821.1 1487392..1488744(-) (vicK) [Streptococcus mutans strain COCC33-14R]
MTNVFESSPLFLRILLAVLIILLFFYFIFLNYREYKNNNQVKQLNAKVRSLITGHYTDKLKVEDNSDLSELVNNVNDLSE
VFRLTHENLAQEKNRLTSILSYMTDGVLATDRRGKITVINDMAQKQLNVTREQALECNILDILDDDSYTYNDLITKTPEI
VLTRRDEYDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMITDLLSLSRIDNQTSHLDVELTNFTAFMNYILDRFDQIQSQQSTNKVYEIIRDYPDKSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKVTVTMQTTDTQLILSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWANSEEGEGSTFTIVLPYENDNDAIDEWEEDEDES

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=713583 NPS17_RS06830 WP_002264821.1 1487392..1488744(-) (vicK) [Streptococcus mutans strain COCC33-14R]
ATGACTAATGTGTTTGAATCAAGTCCCTTATTTTTACGAATTTTATTAGCAGTTTTAATCATTTTACTCTTTTTTTATTT
TATTTTTCTCAATTACAGAGAGTATAAAAATAATAATCAAGTTAAACAGTTAAATGCTAAAGTACGTTCTTTGATTACTG
GCCATTATACTGATAAATTAAAGGTTGAGGATAACTCTGACTTGTCAGAACTAGTGAATAACGTTAATGATTTATCAGAA
GTTTTCCGTTTAACGCATGAAAATTTGGCACAGGAGAAAAACCGTCTGACTAGTATTTTATCTTATATGACAGATGGTGT
TTTGGCAACAGATCGCCGCGGAAAGATTACCGTTATTAACGATATGGCGCAAAAGCAACTGAATGTAACGCGTGAGCAGG
CATTGGAGTGCAATATTCTGGATATTTTGGATGATGATAGTTATACTTACAATGATTTGATTACAAAAACGCCAGAAATT
GTTCTGACGCGGCGTGATGAATATGATGAATTTATCACTTTACGCATTCGTTTTGCCTTAAACCGCCGTGAAAGTGGCTT
TATTTCAGGACTAATTGCTGTCTTGCATGATGCGACCGAACAGGAAAAAGAAGAACGTGAACGCCGTCTCTTTGTTTCTA
ATGTCAGTCATGAACTGCGGACACCATTAACCTCTGTAAAGTCCTATTTAGAAGCTTTGGACGATGGTGCCCTGACAGAA
TCAGTGGCTCCTAGTTTTATCAAGGTATCACTTGATGAGACTAATCGCATGATGCGTATGATTACTGATTTACTTAGCTT
ATCACGTATTGATAATCAGACCAGTCATTTAGATGTTGAATTGACGAATTTTACAGCTTTTATGAATTATATTCTGGATC
GCTTTGATCAAATTCAAAGTCAGCAATCAACTAATAAGGTTTACGAAATTATTAGAGATTATCCTGACAAATCAGTTTGG
ATTGAAATTGATACCGATAAAATGACTCAGGTAATTGATAATATTTTAAATAATGCAATCAAATATTCACCTGATGGCGG
TAAGGTGACTGTAACGATGCAGACAACAGATACACAACTCATCCTTTCTATATCCGACCAAGGCTTGGGTATTCCTAAGA
AGGATCTCCCTCTTATTTTTGACCGTTTTTATCGTGTTGATAAGGCAAGAAGCCGTGCTCAAGGTGGGACTGGTTTAGGA
TTAGCAATCGCCAAAGAAATTGTCAAACAGCATAAAGGCTTTATTTGGGCCAATAGTGAGGAAGGCGAAGGGTCGACCTT
TACCATCGTTTTACCTTATGAAAACGATAATGATGCAATTGATGAATGGGAAGAAGATGAAGACGAATCATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

99.556

100

0.996
  micB Streptococcus pneumoniae Cp1015

67.599

95.333

0.644