Detailed information NTG0713585

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: NPS17_RS06860
• Genome accession: NZ_CP101985
• Coordinates: 1492843..1493724 (-)
• Length: 293 a.a.
• NCBI ID: WP_258968845.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain COCC33-14R
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1487843..1498724

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS17_RS06835 (NPS17_06835)	vicR	1488737..1489444 (-)	708	WP_002262930.1	response regulator YycF	Regulator
NPS17_RS06840 (NPS17_06840)	-	1489797..1490579 (+)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
NPS17_RS06845 (NPS17_06845)	-	1490576..1491388 (+)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
NPS17_RS06850 (NPS17_06850)	-	1491406..1492110 (+)	705	WP_002262933.1	amino acid ABC transporter permease	-
NPS17_RS06855 (NPS17_06855)	-	1492125..1492775 (+)	651	WP_002262934.1	amino acid ABC transporter permease	-
NPS17_RS06860 (NPS17_06860)	endA	1492843..1493724 (-)	882	WP_258968845.1	DNA/RNA non-specific endonuclease	Machinery gene
NPS17_RS06865 (NPS17_06865)	-	1493766..1493954 (-)	189	WP_082999480.1	DNA-directed RNA polymerase subunit beta	-
NPS17_RS06870 (NPS17_06870)	murA	1493957..1495228 (-)	1272	WP_002271905.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
NPS17_RS06875 (NPS17_06875)	-	1495294..1495527 (-)	234	WP_002285829.1	DUF1146 family protein	-
NPS17_RS06880 (NPS17_06880)	-	1495799..1496215 (-)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
NPS17_RS06885 (NPS17_06885)	atpD	1496229..1497635 (-)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
NPS17_RS06890 (NPS17_06890)	-	1497661..1498539 (-)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32183.83 Da
• Isoelectric Point: 9.5337

>NTDB_id=713585 NPS17_RS06860 WP_258968845.1 1492843..1493724(-) (endA) [Streptococcus mutans strain COCC33-14R]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILLNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYANNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=713585 NPS17_RS06860 WP_258968845.1 1492843..1493724(-) (endA) [Streptococcus mutans strain COCC33-14R]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTTAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCTTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAATAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (103-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.378	79.522	0.512
endA	Streptococcus pneumoniae D39	64.378	79.522	0.512
endA	Streptococcus pneumoniae R6	64.378	79.522	0.512
endA	Streptococcus pneumoniae TIGR4	64.378	79.522	0.512