Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   NPS17_RS02920 Genome accession   NZ_CP101985
Coordinates   604886..607120 (+) Length   744 a.a.
NCBI ID   WP_082999655.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 599886..612120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS02895 (NPS17_02895) - 600588..601607 (-) 1020 WP_002275179.1 GIY-YIG nuclease family protein -
  NPS17_RS02900 (NPS17_02900) - 601653..602165 (-) 513 WP_258969077.1 HXXEE domain-containing protein -
  NPS17_RS02905 (NPS17_02905) - 602250..603185 (-) 936 WP_002269713.1 polysaccharide deacetylase family protein -
  NPS17_RS02910 (NPS17_02910) - 603324..604076 (+) 753 WP_002265384.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NPS17_RS02915 (NPS17_02915) - 604216..604896 (+) 681 WP_002265385.1 helix-hairpin-helix domain-containing protein -
  NPS17_RS02920 (NPS17_02920) comEC/celB 604886..607120 (+) 2235 WP_082999655.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NPS17_RS02925 (NPS17_02925) - 607306..607932 (+) 627 WP_082999654.1 DUF805 domain-containing protein -
  NPS17_RS02930 (NPS17_02930) holA 608100..609140 (+) 1041 WP_082999653.1 DNA polymerase III subunit delta -
  NPS17_RS02935 (NPS17_02935) sodA 609287..609898 (+) 612 WP_002265388.1 superoxide dismutase SodA -
  NPS17_RS02940 (NPS17_02940) - 610451..611515 (+) 1065 WP_080037287.1 serine hydrolase -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 85576.01 Da        Isoelectric Point: 10.0891

>NTDB_id=713567 NPS17_RS02920 WP_082999655.1 604886..607120(+) (comEC/celB) [Streptococcus mutans strain COCC33-14R]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSINGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRRRISDANAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGSIRFKGLKHWQIETVR

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=713567 NPS17_RS02920 WP_082999655.1 604886..607120(+) (comEC/celB) [Streptococcus mutans strain COCC33-14R]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGTTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTATCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCAGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTCACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTGCCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGCCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAAAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACCTTTGGACAGACTGATAAATGGCGGCGGCGTATCAGTGATGCTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTTCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(214-460)

Domain of unknown function (DUF4131) (DUF4131)

(30-174)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

51.413

99.866

0.513
  comEC/celB Streptococcus mitis SK321

51.012

99.597

0.508
  comEC/celB Streptococcus pneumoniae TIGR4

50.538

100

0.505
  comEC/celB Streptococcus pneumoniae Rx1

49.866

100

0.499
  comEC/celB Streptococcus pneumoniae D39

49.866

100

0.499
  comEC/celB Streptococcus pneumoniae R6

49.866

100

0.499
  comEC Lactococcus lactis subsp. cremoris KW2

46.04

100

0.461