Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CHBNTHi_RS04080 Genome accession   NZ_AP018781
Coordinates   799464..800684 (+) Length   406 a.a.
NCBI ID   WP_005666687.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-V-1 isolate 13H43     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 794464..805684
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CHBNTHi_RS04060 (CHBNV1_07820) corC 795430..796329 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  CHBNTHi_RS04065 (CHBNV1_07830) ampD 796952..797512 (-) 561 WP_075985522.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CHBNTHi_RS04070 (CHBNV1_07840) pilA 797627..798076 (+) 450 WP_005666683.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CHBNTHi_RS04075 (CHBNV1_07850) pilB 798073..799467 (+) 1395 WP_005666685.1 GspE/PulE family protein Machinery gene
  CHBNTHi_RS04080 (CHBNV1_07860) pilC 799464..800684 (+) 1221 WP_005666687.1 type II secretion system F family protein Machinery gene
  CHBNTHi_RS04085 (CHBNV1_07870) pilD 800681..801373 (+) 693 WP_005666688.1 A24 family peptidase Machinery gene
  CHBNTHi_RS04090 (CHBNV1_07880) rho 801428..802690 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  CHBNTHi_RS04095 (CHBNV1_07890) metJ 802938..803255 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  CHBNTHi_RS04100 (CHBNV1_07900) cueR 803269..803655 (-) 387 WP_038439225.1 Cu(I)-responsive transcriptional regulator -
  CHBNTHi_RS04105 (CHBNV1_07910) - 803732..803938 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  CHBNTHi_RS04110 (CHBNV1_07920) - 804024..804230 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46207.43 Da        Isoelectric Point: 9.8218

>NTDB_id=71324 CHBNTHi_RS04080 WP_005666687.1 799464..800684(+) (pilC) [Haemophilus influenzae strain CHBN-V-1 isolate 13H43]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMVYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQQKNQLISVTPIFGTIQKLSRLVNFSRSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=71324 CHBNTHi_RS04080 WP_005666687.1 799464..800684(+) (pilC) [Haemophilus influenzae strain CHBN-V-1 isolate 13H43]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCGCACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGGTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGTTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCGCAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTTTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment