Detailed information NTG0709517

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: PGH47_RS11840
• Genome accession: NZ_CP116353
• Coordinates: 2680008..2681093 (+)
• Length: 361 a.a.
• NCBI ID: WP_271663385.1
• Uniprot ID: -
• Organism: Streptomyces sp. HUAS 31
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2675008..2686093

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PGH47_RS11810 (PGH47_11810)	-	2675014..2675694 (-)	681	WP_271663382.1	response regulator transcription factor	-
PGH47_RS11815 (PGH47_11815)	-	2675777..2676994 (-)	1218	WP_271663383.1	sensor histidine kinase	-
PGH47_RS11820 (PGH47_11820)	-	2677093..2677371 (-)	279	WP_271668031.1	hypothetical protein	-
PGH47_RS11825 (PGH47_11825)	-	2677420..2678187 (-)	768	WP_260609300.1	PspA/IM30 family protein	-
PGH47_RS11830 (PGH47_11830)	-	2678489..2679127 (+)	639	WP_125525241.1	DUF3043 domain-containing protein	-
PGH47_RS11835 (PGH47_11835)	-	2679211..2679951 (+)	741	WP_271663384.1	methyltransferase domain-containing protein	-
PGH47_RS11840 (PGH47_11840)	htrA	2680008..2681093 (+)	1086	WP_271663385.1	trypsin-like peptidase domain-containing protein	Regulator
PGH47_RS11845 (PGH47_11845)	-	2681131..2681340 (-)	210	WP_030967709.1	hypothetical protein	-
PGH47_RS11850 (PGH47_11850)	-	2681456..2682658 (+)	1203	WP_271663386.1	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	-
PGH47_RS11855 (PGH47_11855)	-	2682772..2683593 (-)	822	WP_271663387.1	class I SAM-dependent methyltransferase	-
PGH47_RS11860 (PGH47_11860)	cobT	2683808..2684917 (+)	1110	WP_271663388.1	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	-
PGH47_RS11865 (PGH47_11865)	-	2684972..2685676 (+)	705	WP_271663389.1	hypothetical protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 37042.27 Da
• Isoelectric Point: 4.3115

>NTDB_id=709517 PGH47_RS11840 WP_271663385.1 2680008..2681093(+) (htrA) [Streptomyces sp. HUAS 31]
MDARRLRTRRPVVAVLALLCCLGLLSACSSSPFSSSSREEGDSTTQAALPRTPRAVDDLQDGYLKVIRSVLPSVVQIQGR
RDLGSGVVYDDQGHIVTNAHVVGDEKTFRVTTAGSEKELTAQLVSSYPQQDLAVVKLQDPPDGLKAAKFGDSSKVEVGQI
VLAMGSPLGLSSSVTQGIVSATGRTVTEGGDGTTGATIANMVQTSAAINPGNSGGALVNLDSEVIGVPTLAAVDPDVGNS
AAPGIGFAIPASTVRNIADQIIEDGRVTDSGRAALGITGRTVVNDDYQAAGVAVVEVQEGGAADEAGLEPGDIITRLGDT
EITTITSLSEALAGDKPGDETTVTYTRDGDRKKADVTLGEQ

Nucleotide

• Length: 1086 bp

>NTDB_id=709517 PGH47_RS11840 WP_271663385.1 2680008..2681093(+) (htrA) [Streptomyces sp. HUAS 31]
ATGGATGCTCGCCGTTTGCGGACCCGGCGTCCGGTCGTCGCGGTCCTCGCCCTGCTGTGCTGCCTCGGCCTCCTGTCGGC
CTGTTCGTCCTCCCCCTTCTCCTCGTCGTCGCGTGAGGAGGGGGACTCGACGACCCAGGCCGCCCTGCCGAGGACACCCC
GGGCGGTGGACGACCTCCAGGACGGCTATCTGAAGGTGATCAGGAGCGTGCTGCCGTCGGTCGTGCAGATCCAGGGCAGA
CGTGATCTGGGGTCGGGCGTGGTCTACGACGACCAGGGGCACATCGTCACCAACGCGCACGTCGTCGGCGACGAGAAGAC
CTTCCGGGTGACGACCGCCGGCAGCGAGAAGGAGCTCACCGCCCAGCTGGTGTCCTCCTATCCGCAGCAGGACCTCGCCG
TGGTCAAGCTCCAGGACCCGCCGGACGGGCTGAAGGCGGCGAAGTTCGGGGACTCCTCGAAGGTCGAGGTGGGGCAGATC
GTGCTGGCGATGGGCTCGCCGCTCGGGCTGTCGTCCAGCGTGACGCAGGGCATCGTCTCGGCGACCGGACGGACCGTCAC
CGAGGGCGGCGACGGCACCACGGGCGCGACGATCGCCAACATGGTCCAGACGTCTGCGGCCATCAACCCCGGCAACAGCG
GTGGCGCCCTGGTGAACCTCGACAGCGAGGTCATCGGCGTGCCGACGCTGGCCGCCGTGGACCCGGACGTCGGGAACAGC
GCGGCGCCCGGCATCGGGTTCGCGATCCCCGCGTCGACGGTGCGCAACATCGCCGACCAGATCATCGAGGACGGCCGGGT
CACCGACTCGGGCCGGGCCGCGCTCGGCATCACCGGCCGTACCGTCGTCAACGACGACTATCAGGCGGCCGGCGTGGCCG
TGGTCGAGGTGCAGGAGGGCGGGGCGGCCGACGAGGCCGGTCTGGAGCCCGGCGACATCATCACCCGGCTGGGGGACACG
GAGATCACCACCATCACCTCGCTGTCCGAGGCACTGGCCGGCGACAAGCCGGGGGACGAGACGACGGTGACCTACACCCG
CGACGGTGACCGGAAGAAGGCCGATGTGACGCTGGGCGAACAGTGA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (84-227)

• PDZ domain (PDZ_2) (276-358)

• Peptidase family M50 (Peptidase_M50) (277-358)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	34.301	100	0.36