Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   H7679_RS00755 Genome accession   NZ_AP023392
Coordinates   122284..123321 (+) Length   345 a.a.
NCBI ID   WP_050573097.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT300     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117284..128321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS00740 (DAT300_01130) - 119986..120351 (+) 366 WP_024395451.1 DUF1033 family protein -
  H7679_RS00745 (DAT300_01140) - 120386..121336 (-) 951 WP_024395450.1 S66 peptidase family protein -
  H7679_RS00750 (DAT300_01150) comGA 121422..122372 (+) 951 WP_024382125.1 competence type IV pilus ATPase ComGA Machinery gene
  H7679_RS00755 (DAT300_01160) comGB 122284..123321 (+) 1038 WP_050573097.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7679_RS00760 (DAT300_01170) - 123402..124841 (-) 1440 WP_172077518.1 recombinase family protein -
  H7679_RS00765 (DAT300_01180) - 124976..125545 (-) 570 WP_197970253.1 hypothetical protein -
  H7679_RS00770 (DAT300_01190) - 125559..126317 (-) 759 WP_105131553.1 helix-turn-helix domain-containing protein -
  H7679_RS00775 (DAT300_01200) - 126517..126720 (+) 204 WP_105131554.1 helix-turn-helix domain-containing protein -
  H7679_RS00780 (DAT300_01210) - 126775..127032 (+) 258 WP_105131555.1 hypothetical protein -
  H7679_RS00785 (DAT300_01220) - 127008..127154 (+) 147 WP_184495818.1 BOW99_gp33 family protein -
  H7679_RS00790 (DAT300_01230) - 127197..127544 (+) 348 WP_105131556.1 transcriptional regulator -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38938.94 Da        Isoelectric Point: 9.3127

>NTDB_id=70708 H7679_RS00755 WP_050573097.1 122284..123321(+) (comGB) [Streptococcus suis strain DAT300]
MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLVFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQIYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVAVMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=70708 H7679_RS00755 WP_050573097.1 122284..123321(+) (comGB) [Streptococcus suis strain DAT300]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTTATTGAGCTGTTTAACAATCTCTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GTAGCCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCGGATGGCCTTCTTGCAGGAAAGCCATTTTCAAGCCTCTTA
GCTGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTAGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAATTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TGGTTTTTTTGCTCTTGATTATGCTGGGTTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACAGTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCGTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus gordonii str. Challis substr. CH1

63.158

99.13

0.626
  comGB Streptococcus mutans UA140

59.531

98.841

0.588
  comGB Streptococcus mutans UA159

59.531

98.841

0.588
  comGB/cglB Streptococcus mitis NCTC 12261

59.701

97.101

0.58
  comGB/cglB Streptococcus mitis SK321

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae Rx1

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae D39

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae R6

59.104

97.101

0.574
  comGB/cglB Streptococcus pneumoniae TIGR4

59.104

97.101

0.574
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment