Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FGCSD_RS07850 Genome accession   NZ_AP018726
Coordinates   1574829..1576181 (-) Length   450 a.a.
NCBI ID   WP_129556028.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain Kdys0611     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1569829..1581181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGCSD_RS11100 (FGCSD_1520) - 1569851..1570162 (-) 312 Protein_1486 hypothetical protein -
  FGCSD_RS07835 (FGCSD_1523) - 1571825..1572847 (-) 1023 WP_129555386.1 IS30 family transposase -
  FGCSD_RS07840 (FGCSD_1524) - 1573059..1573934 (+) 876 WP_129556026.1 helix-turn-helix transcriptional regulator -
  FGCSD_RS07845 (FGCSD_1525) vicX 1574016..1574825 (-) 810 WP_129556027.1 MBL fold metallo-hydrolase Regulator
  FGCSD_RS07850 (FGCSD_1526) vicK 1574829..1576181 (-) 1353 WP_129556028.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGCSD_RS07855 (FGCSD_1527) vicR 1576174..1576884 (-) 711 WP_003049952.1 response regulator YycF Regulator
  FGCSD_RS07860 (FGCSD_1528) - 1577143..1577937 (+) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  FGCSD_RS07865 (FGCSD_1529) - 1577937..1578737 (+) 801 WP_129556029.1 transporter substrate-binding domain-containing protein -
  FGCSD_RS07870 (FGCSD_1530) - 1578751..1579452 (+) 702 WP_129556030.1 amino acid ABC transporter permease -
  FGCSD_RS07875 (FGCSD_1531) - 1579467..1580114 (+) 648 WP_129556031.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51451.95 Da        Isoelectric Point: 5.5536

>NTDB_id=70592 FGCSD_RS07850 WP_129556028.1 1574829..1576181(-) (vicK) [Streptococcus dysgalactiae strain Kdys0611]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTSV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=70592 FGCSD_RS07850 WP_129556028.1 1574829..1576181(-) (vicK) [Streptococcus dysgalactiae strain Kdys0611]
ATGACTAGAGATATCATCGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCTCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGCAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGTCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTGCGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACTCCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCAAG
GAAGATATTGCCCCAAGTTTTATCAAGGTTTCTCTTGATGAAACCAATCGTATGATGCGAATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTTGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACTTCT
GTTTGGCTGGAAATTGATAACGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACAGACACGCAATTGATTATTTCCATCTCAGACCAAGGTTTAGGCATTC
CGAAGAAGGACCTGCCCCTTATTTTTGACCGTTTTTACCGAGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATCTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGACGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-157)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.43

92

0.676
  micB Streptococcus pneumoniae Cp1015

66.588

94.444

0.629

Multiple sequence alignment