Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   NLY75_RS06760 Genome accession   NZ_CP100432
Coordinates   1342635..1344872 (-) Length   745 a.a.
NCBI ID   WP_023370710.1    Uniprot ID   A0A822VNS2
Organism   Streptococcus suis T15     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1337635..1349872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY75_RS06730 (NLY75_06730) tmk 1337751..1338389 (-) 639 WP_023370703.1 dTMP kinase -
  NLY75_RS06735 (NLY75_06735) - 1338564..1339430 (+) 867 WP_023370705.1 YitT family protein -
  NLY75_RS06740 (NLY75_06740) - 1339467..1340738 (-) 1272 WP_002935355.1 toxic anion resistance protein -
  NLY75_RS06745 (NLY75_06745) - 1340744..1341571 (-) 828 WP_023370707.1 hypothetical protein -
  NLY75_RS06750 (NLY75_06750) - 1341665..1342321 (-) 657 WP_023370708.1 CBS domain-containing protein -
  NLY75_RS06755 (NLY75_06755) - 1342504..1342626 (-) 123 Protein_1288 IS982 family transposase -
  NLY75_RS06760 (NLY75_06760) comEC/celB 1342635..1344872 (-) 2238 WP_023370710.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NLY75_RS06765 (NLY75_06765) comEA/celA/cilE 1344856..1345518 (-) 663 WP_023370712.1 helix-hairpin-helix domain-containing protein Machinery gene
  NLY75_RS06770 (NLY75_06770) - 1345585..1346331 (-) 747 WP_023370714.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NLY75_RS06775 (NLY75_06775) - 1346477..1347922 (+) 1446 WP_023370716.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  NLY75_RS06780 (NLY75_06780) - 1348074..1348874 (+) 801 WP_023370718.1 ABC transporter ATP-binding protein -
  NLY75_RS06785 (NLY75_06785) - 1348871..1349800 (+) 930 WP_023370720.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84161.27 Da        Isoelectric Point: 8.9144

>NTDB_id=705323 NLY75_RS06760 WP_023370710.1 1342635..1344872(-) (comEC/celB) [Streptococcus suis T15]
MSRLSKLPCQPIHLALLAVAAYFVVHSFSLLTMGLLSLLLLVFGFRQGKTVFIRTLPLIALCGLFFGYQKVQWERADQLA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPVPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGKNNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=705323 NLY75_RS06760 WP_023370710.1 1342635..1344872(-) (comEC/celB) [Streptococcus suis T15]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATCCACTTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGACAAGGTAAGACAGTTTTCATCA
GAACGCTGCCGCTTATAGCCTTATGTGGTCTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGACAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGTCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTACCTG
AAAACACAGGGTATTTATCGGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGTTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCAGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGATGGGACAGGAGACGGTGGTAATAATGACTCTATTGTTCTCTACGGTCGCTTGTTG
GAAACCAACTTTCTCTTTACAGGAGATTTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAGGCTGGTCACCATGGCTCCAAAGGTTCTTCCTATCCCGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGATATCTGCTGGAAAAAATAACCGCTACAAGCATCCTCATCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A822VNS2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.24

99.732

0.541
  comEC/celB Streptococcus mitis NCTC 12261

53.171

99.463

0.529
  comEC/celB Streptococcus pneumoniae TIGR4

52.291

99.597

0.521
  comEC/celB Streptococcus pneumoniae Rx1

52.022

99.597

0.518
  comEC/celB Streptococcus pneumoniae D39

52.022

99.597

0.518
  comEC/celB Streptococcus pneumoniae R6

52.022

99.597

0.518
  comEC Lactococcus lactis subsp. cremoris KW2

49.398

100

0.495