Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NLY76_RS04055 Genome accession   NZ_CP100430
Coordinates   832551..833930 (+) Length   459 a.a.
NCBI ID   WP_014635993.1    Uniprot ID   -
Organism   Streptococcus suis strain LSS42     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 827551..838930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS04025 (NLY76_04025) pstA 827977..828864 (+) 888 WP_044757644.1 phosphate ABC transporter permease PstA -
  NLY76_RS04030 (NLY76_04030) pstB 828889..829692 (+) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -
  NLY76_RS04035 (NLY76_04035) pstB 829704..830462 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  NLY76_RS04040 (NLY76_04040) phoU 830491..831147 (+) 657 WP_044769841.1 phosphate signaling complex protein PhoU -
  NLY76_RS04045 (NLY76_04045) - 831313..831693 (+) 381 WP_044666718.1 hypothetical protein -
  NLY76_RS04050 (NLY76_04050) ciaR 831887..832558 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  NLY76_RS04055 (NLY76_04055) ciaH 832551..833930 (+) 1380 WP_014635993.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NLY76_RS04060 (NLY76_04060) - 834030..835259 (+) 1230 WP_044769839.1 transglutaminase domain-containing protein -
  NLY76_RS04065 (NLY76_04065) rpsT 835524..835772 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  NLY76_RS04070 (NLY76_04070) coaA 835831..836751 (-) 921 WP_044684617.1 type I pantothenate kinase -
  NLY76_RS04075 (NLY76_04075) - 836860..837450 (+) 591 WP_014637855.1 class I SAM-dependent methyltransferase -
  NLY76_RS04080 (NLY76_04080) - 837447..838724 (+) 1278 WP_002940851.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51926.60 Da        Isoelectric Point: 6.8975

>NTDB_id=705214 NLY76_RS04055 WP_014635993.1 832551..833930(+) (ciaH) [Streptococcus suis strain LSS42]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKEAMVESSFGM
SEDYRYVTIELPTDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDT
DRKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=705214 NLY76_RS04055 WP_014635993.1 832551..833930(+) (ciaH) [Streptococcus suis strain LSS42]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCAACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAATGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGCCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCTTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCAAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACTGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATACC
GATAGGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

48.922

100

0.495
  ciaH Streptococcus pneumoniae D39

48.922

100

0.495
  ciaH Streptococcus pneumoniae R6

48.922

100

0.495
  ciaH Streptococcus pneumoniae TIGR4

48.922

100

0.495
  ciaH Streptococcus mutans UA159

49.888

97.386

0.486