Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   PDI73_RS00220 Genome accession   NZ_CP115479
Coordinates   47273..48715 (-) Length   480 a.a.
NCBI ID   WP_010905315.1    Uniprot ID   Q9CIG6
Organism   Lactococcus lactis strain EP2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 42273..53715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PDI73_RS00195 (PDI73_00195) - 42306..43646 (+) 1341 WP_023188995.1 FAD-dependent oxidoreductase -
  PDI73_RS00200 (PDI73_00200) - 43736..44125 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  PDI73_RS00205 (PDI73_00205) groES 44245..44529 (+) 285 WP_003131589.1 co-chaperone GroES -
  PDI73_RS00210 (PDI73_00210) groL 44617..46245 (+) 1629 WP_003131585.1 chaperonin GroEL -
  PDI73_RS00215 (PDI73_00215) vicX 46292..47104 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  PDI73_RS00220 (PDI73_00220) vicK 47273..48715 (-) 1443 WP_010905315.1 cell wall metabolism sensor histidine kinase WalK Regulator
  PDI73_RS00225 (PDI73_00225) yycF 48708..49409 (-) 702 WP_003131580.1 response regulator YycF -
  PDI73_RS00230 (PDI73_00230) tmk 49587..50222 (+) 636 WP_012897230.1 dTMP kinase -
  PDI73_RS00235 (PDI73_00235) - 50355..51215 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  PDI73_RS00240 (PDI73_00240) yaaT 51267..52049 (+) 783 WP_010905316.1 stage 0 sporulation family protein Regulator
  PDI73_RS00245 (PDI73_00245) yabA 52042..52368 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  PDI73_RS00250 (PDI73_00250) rsmI 52368..53243 (+) 876 WP_033900473.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  PDI73_RS00255 (PDI73_00255) - 53320..53511 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54695.14 Da        Isoelectric Point: 4.5889

>NTDB_id=704760 PDI73_RS00220 WP_010905315.1 47273..48715(-) (vicK) [Lactococcus lactis strain EP2]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=704760 PDI73_RS00220 WP_010905315.1 47273..48715(-) (vicK) [Lactococcus lactis strain EP2]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCCCACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGTGATAAAATC
CCAAAAGGGACAAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTCGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTTTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CIG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442