Detailed information NTG0704535

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: NKZ66_RS00815
• Genome accession: NZ_CP100336
• Coordinates: 128915..129349 (+)
• Length: 144 a.a.
• NCBI ID: WP_063725150.1
• Uniprot ID: -
• Organism: Streptococcus suis strain STC81
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 123915..134349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ66_RS00780 (NKZ66_00780)	-	124657..125022 (+)	366	WP_024417409.1	DUF1033 family protein	-
NKZ66_RS00785 (NKZ66_00785)	-	125057..126007 (-)	951	WP_024417410.1	S66 peptidase family protein	-
NKZ66_RS00790 (NKZ66_00790)	comYA	126093..127043 (+)	951	WP_024417411.1	competence type IV pilus ATPase ComGA	Machinery gene
NKZ66_RS00795 (NKZ66_00795)	comYB	126955..127992 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
NKZ66_RS00800 (NKZ66_00800)	comYC	127994..128275 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
NKZ66_RS00805 (NKZ66_00805)	comGD	128256..128663 (+)	408	WP_024387070.1	competence type IV pilus minor pilin ComGD	-
NKZ66_RS00810 (NKZ66_00810)	comYE	128635..128928 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
NKZ66_RS00815 (NKZ66_00815)	comGF/cglF	128915..129349 (+)	435	WP_063725150.1	competence type IV pilus minor pilin ComGF	Machinery gene
NKZ66_RS00820 (NKZ66_00820)	comGG	129327..129737 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
NKZ66_RS00825 (NKZ66_00825)	comYH	129794..130747 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
NKZ66_RS00830 (NKZ66_00830)	-	130797..131984 (+)	1188	WP_014637319.1	acetate kinase	-
NKZ66_RS00835 (NKZ66_00835)	-	132299..132850 (+)	552	WP_024417413.1	folate family ECF transporter S component	-
NKZ66_RS00840 (NKZ66_00840)	-	132906..134162 (+)	1257	WP_024417414.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16420.77 Da
• Isoelectric Point: 6.9834

>NTDB_id=704535 NKZ66_RS00815 WP_063725150.1 128915..129349(+) (comGF/cglF) [Streptococcus suis strain STC81]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVDKDG
QALAFGKSRSDDFRKTNDRGQGYQPMLYQVDSAAISQEKQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=704535 NKZ66_RS00815 WP_063725150.1 128915..129349(+) (comGF/cglF) [Streptococcus suis strain STC81]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCCTTAGTCATCCTTTCAGGTAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCGATAAGGATGGA
CAAGCATTAGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGTTACCAGCCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAAGCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae Rx1	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae D39	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae R6	53.901	97.917	0.528
comGF/cglF	Streptococcus mitis NCTC 12261	54.478	93.056	0.507
comYF	Streptococcus mutans UA140	50	100	0.5
comYF	Streptococcus mutans UA159	49.306	100	0.493
comGF/cglF	Streptococcus mitis SK321	51.493	93.056	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	47.518	97.917	0.465