Detailed information NTG0704445

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NKZ65_RS06100
• Genome accession: NZ_CP100332
• Coordinates: 1215028..1217265 (-)
• Length: 745 a.a.
• NCBI ID: WP_044752722.1
• Uniprot ID: -
• Organism: Streptococcus suis strain STC84
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1210028..1222265

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ65_RS06070 (NKZ65_06070)	tmk	1210145..1210783 (-)	639	WP_002935358.1	dTMP kinase	-
NKZ65_RS06075 (NKZ65_06075)	-	1210958..1211824 (+)	867	WP_002935357.1	YitT family protein	-
NKZ65_RS06080 (NKZ65_06080)	-	1211861..1213132 (-)	1272	WP_002935355.1	toxic anion resistance protein	-
NKZ65_RS06085 (NKZ65_06085)	-	1213138..1213965 (-)	828	WP_024417275.1	hypothetical protein	-
NKZ65_RS06090 (NKZ65_06090)	-	1214058..1214714 (-)	657	WP_023370708.1	CBS domain-containing protein	-
NKZ65_RS06095 (NKZ65_06095)	-	1214897..1215019 (-)	123	Protein_1154	IS982 family transposase	-
NKZ65_RS06100 (NKZ65_06100)	comEC/celB	1215028..1217265 (-)	2238	WP_044752722.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NKZ65_RS06105 (NKZ65_06105)	comEA/celA/cilE	1217249..1217911 (-)	663	WP_079394055.1	helix-hairpin-helix domain-containing protein	Machinery gene
NKZ65_RS06110 (NKZ65_06110)	-	1217981..1218727 (-)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NKZ65_RS06115 (NKZ65_06115)	-	1218874..1220319 (+)	1446	WP_172001200.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
NKZ65_RS06120 (NKZ65_06120)	-	1220471..1221271 (+)	801	WP_172001201.1	ABC transporter ATP-binding protein	-
NKZ65_RS06125 (NKZ65_06125)	-	1221268..1222197 (+)	930	WP_172001202.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84145.26 Da
• Isoelectric Point: 7.3815

>NTDB_id=704445 NKZ65_RS06100 WP_044752722.1 1215028..1217265(-) (comEC/celB) [Streptococcus suis strain STC84]
MLRSIKLPCQPIHLALLAVAAYFVVRSFSLLTMGLLSLVLAVFGVRQGKAVFLRTLPLLALCGLFFGFQKLQWNRADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQELADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCFLLL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMIYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIIKITWVNGFFVLMEKIIVWVADLGLRPWILGKPSVVILILLLVCLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFMRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVHIGRIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALISAGENNRYKHPHQETLDRFDSRDIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=704445 NKZ65_RS06100 WP_044752722.1 1215028..1217265(-) (comEC/celB) [Streptococcus suis strain STC84]
ATGTTACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCGCTC
TTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGGCAGTTTTCCTCA
GAACGCTGCCGCTTCTAGCCCTGTGTGGTCTCTTTTTCGGATTTCAAAAGCTTCAATGGAATCGAGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTCCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACAGTTTTTGTCTGTTTCTTGTTGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTGATGATCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACTTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAATTATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGTGGTAATTCTTATTCTCTTGCTGGTCTGTCTCTTCT
TACTTTATGATTTCCACAGAAAAAAGAAATGGCTCTTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGTGACAGCATCTTTATGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTTCTGACACACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTCCATATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATTAATGTGCCTGTCCATGTGGTCAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGATATCTGCTGGAGAAAATAACCGCTACAAGCATCCACACCAAGAAACCTTGGACCGCTTTGATAGTCGAGATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-172)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.24	99.732	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.467	100	0.538
comEC/celB	Streptococcus pneumoniae TIGR4	52.463	100	0.529
comEC/celB	Streptococcus pneumoniae Rx1	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae D39	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae R6	52.197	100	0.526
comEC	Lactococcus lactis subsp. cremoris KW2	49.332	100	0.495