Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   NEE09_RS00370 Genome accession   NZ_CP099641
Coordinates   66388..67050 (+) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 61388..72050
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS00340 tnpB 61947..62162 (+) 216 WP_000376909.1 IS66 family insertion sequence element accessory protein TnpB -
  NEE09_RS00345 - 62303..62611 (-) 309 Protein_61 transposase -
  NEE09_RS00350 - 62584..63122 (+) 539 Protein_62 transposase -
  NEE09_RS00355 cysK 63197..64117 (-) 921 WP_000029866.1 cysteine synthase A -
  NEE09_RS00360 - 64402..65037 (-) 636 WP_000395738.1 YigZ family protein -
  NEE09_RS00365 comFA/cflA 65093..66391 (+) 1299 WP_000867591.1 DEAD/DEAH box helicase Machinery gene
  NEE09_RS00370 comFC/cflB 66388..67050 (+) 663 WP_000649971.1 ComF family protein Machinery gene
  NEE09_RS00375 hpf 67130..67678 (+) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  NEE09_RS00380 - 67814..69787 (+) 1974 WP_000715116.1 DHH family phosphoesterase -
  NEE09_RS00385 rplI 69784..70236 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  NEE09_RS00390 dnaB 70280..71632 (+) 1353 WP_000852486.1 replicative DNA helicase -
  NEE09_RS00395 - 71634..71900 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=701161 NEE09_RS00370 WP_000649971.1 66388..67050(+) (comFC/cflB) [Streptococcus pneumoniae strain ATCC 700671]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=701161 NEE09_RS00370 WP_000649971.1 66388..67050(+) (comFC/cflB) [Streptococcus pneumoniae strain ATCC 700671]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914