Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SA27298_RS08210 Genome accession   NZ_AP018548
Coordinates   1683424..1683717 (-) Length   97 a.a.
NCBI ID   WP_003032294.1    Uniprot ID   -
Organism   Streptococcus anginosus strain CCUG 27928     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1678424..1688717
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS08190 (SA27298_1670) - 1680412..1681611 (-) 1200 WP_003032291.1 acetate kinase -
  SA27298_RS08195 (SA27298_1671) comYH 1681658..1682611 (-) 954 WP_003032282.1 class I SAM-dependent methyltransferase Machinery gene
  SA27298_RS08200 (SA27298_1672) comGG 1682696..1683022 (-) 327 WP_018543596.1 competence type IV pilus minor pilin ComGG -
  SA27298_RS08205 (SA27298_1673) comGF/cglF 1683003..1683440 (-) 438 WP_003032293.1 competence type IV pilus minor pilin ComGF Machinery gene
  SA27298_RS08210 (SA27298_1674) comGE/cglE 1683424..1683717 (-) 294 WP_003032294.1 competence type IV pilus minor pilin ComGE Machinery gene
  SA27298_RS08215 (SA27298_1675) comYD 1683689..1684087 (-) 399 WP_003032289.1 competence type IV pilus minor pilin ComGD Machinery gene
  SA27298_RS08220 (SA27298_1676) comYC 1684077..1684394 (-) 318 WP_003026997.1 competence type IV pilus major pilin ComGC Machinery gene
  SA27298_RS08225 (SA27298_1677) comYB 1684391..1685413 (-) 1023 WP_037582505.1 competence type IV pilus assembly protein ComGB Machinery gene
  SA27298_RS08230 (SA27298_1678) comYA 1685355..1686296 (-) 942 WP_003032308.1 competence type IV pilus ATPase ComGA Machinery gene
  SA27298_RS08235 (SA27298_1679) - 1686366..1686731 (-) 366 WP_003032307.1 DUF1033 family protein -
  SA27298_RS08240 (SA27298_1680) glnA 1686919..1688265 (-) 1347 WP_003032299.1 type I glutamate--ammonia ligase -
  SA27298_RS08245 (SA27298_1681) - 1688304..1688663 (-) 360 WP_003028467.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10941.89 Da        Isoelectric Point: 10.8025

>NTDB_id=70002 SA27298_RS08210 WP_003032294.1 1683424..1683717(-) (comGE/cglE) [Streptococcus anginosus strain CCUG 27928]
MGNLRKQRVRGTILLEALLALAVFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIKVRVETSQQ
GIQIYHGRELILDVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=70002 SA27298_RS08210 WP_003032294.1 1683424..1683717(-) (comGE/cglE) [Streptococcus anginosus strain CCUG 27928]
ATGGGAAATTTAAGAAAACAACGCGTTAGAGGAACGATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAAACAAAGCAAAGTCATCTGACAATGAATGGTATTAAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAGATTTATCATGGAAGGGAACTAATTCTTGATGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae D39

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae R6

52.632

97.938

0.515
  comGE/cglE Streptococcus pneumoniae TIGR4

52.632

97.938

0.515
  comGE/cglE Streptococcus mitis NCTC 12261

51.579

97.938

0.505
  comGE/cglE Streptococcus mitis SK321

51.579

97.938

0.505
  comYE Streptococcus mutans UA140

43.434

100

0.443
  comYE Streptococcus mutans UA159

43.434

100

0.443

Multiple sequence alignment