Detailed information NTG0070000

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: SA27298_RS08195
• Genome accession: NZ_AP018548
• Coordinates: 1681658..1682611 (-)
• Length: 317 a.a.
• NCBI ID: WP_003032282.1
• Uniprot ID: A0A448AK79
• Organism: Streptococcus anginosus strain CCUG 27928
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1676658..1687611

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA27298_RS08185 (SA27298_1669)	glmS	1678209..1680023 (-)	1815	WP_022524764.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
SA27298_RS08190 (SA27298_1670)	-	1680412..1681611 (-)	1200	WP_003032291.1	acetate kinase	-
SA27298_RS08195 (SA27298_1671)	comYH	1681658..1682611 (-)	954	WP_003032282.1	class I SAM-dependent methyltransferase	Machinery gene
SA27298_RS08200 (SA27298_1672)	comGG	1682696..1683022 (-)	327	WP_018543596.1	competence type IV pilus minor pilin ComGG	-
SA27298_RS08205 (SA27298_1673)	comGF/cglF	1683003..1683440 (-)	438	WP_003032293.1	competence type IV pilus minor pilin ComGF	Machinery gene
SA27298_RS08210 (SA27298_1674)	comGE/cglE	1683424..1683717 (-)	294	WP_003032294.1	competence type IV pilus minor pilin ComGE	Machinery gene
SA27298_RS08215 (SA27298_1675)	comYD	1683689..1684087 (-)	399	WP_003032289.1	competence type IV pilus minor pilin ComGD	Machinery gene
SA27298_RS08220 (SA27298_1676)	comYC	1684077..1684394 (-)	318	WP_003026997.1	competence type IV pilus major pilin ComGC	Machinery gene
SA27298_RS08225 (SA27298_1677)	comYB	1684391..1685413 (-)	1023	WP_037582505.1	competence type IV pilus assembly protein ComGB	Machinery gene
SA27298_RS08230 (SA27298_1678)	comYA	1685355..1686296 (-)	942	WP_003032308.1	competence type IV pilus ATPase ComGA	Machinery gene
SA27298_RS08235 (SA27298_1679)	-	1686366..1686731 (-)	366	WP_003032307.1	DUF1033 family protein	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36123.92 Da
• Isoelectric Point: 4.2586

>NTDB_id=70000 SA27298_RS08195 WP_003032282.1 1681658..1682611(-) (comYH) [Streptococcus anginosus strain CCUG 27928]
MNFEKIEQTYMLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTQKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDNIATRYEVASRQEHTYAHHLLMEQSLKYLKSGGYAIFLAPNDLLTSSQ
SDLLKTWLQKHAQIVAMIALPEALFGNAAYAKTIFVLQKQEEQAVQLFVYALSDLRDQDDLLEFSEKFQNWSRESEI

Nucleotide

• Length: 954 bp

>NTDB_id=70000 SA27298_RS08195 WP_003032282.1 1681658..1682611(-) (comYH) [Streptococcus anginosus strain CCUG 27928]
ATGAATTTTGAAAAAATTGAACAGACCTATATGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATCTGGACGGGGATATTGAACTAGATAGTGTTCGGCAGAATAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAGGAATGGCGCCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCTGAGACGATTCTCAATAATACACAAAAAA
ATGTGGATTATCTAGGACTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCAGTGCGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAACATTGCGACGCGCTATGAAGTGGCTAGTAGACAGGAGCATACTTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCAGGCGGTTATGCTATTTTCCTTGCACCAAATGATTTATTGACTAGTTCGCAA
AGTGATTTGCTGAAAACTTGGCTGCAAAAGCATGCCCAGATAGTTGCGATGATTGCATTGCCAGAAGCACTTTTTGGAAA
TGCCGCTTATGCCAAGACAATTTTTGTGCTGCAAAAGCAAGAAGAACAAGCTGTTCAACTGTTTGTTTATGCTTTGTCTG
ATTTGCGAGATCAGGACGATTTATTGGAATTTAGCGAAAAGTTTCAAAATTGGAGCAGAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-299)

3D structure

• AlphaFold DB: A0A448AK79

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	61.27	99.369	0.609
comYH	Streptococcus mutans UA159	60.952	99.369	0.606