Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SR187_RS02935 Genome accession   NZ_AP018400
Coordinates   584673..586022 (+) Length   449 a.a.
NCBI ID   WP_024532081.1    Uniprot ID   A0A2Z5TLH3
Organism   Streptococcus ruminantium strain GUT-187     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 579673..591022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS02910 (SR187_2960) - 580789..581448 (-) 660 WP_120171455.1 amino acid ABC transporter permease -
  SR187_RS02915 (SR187_2965) - 581461..582159 (-) 699 WP_120171456.1 amino acid ABC transporter permease -
  SR187_RS02920 (SR187_2970) - 582174..583010 (-) 837 WP_120171457.1 transporter substrate-binding domain-containing protein -
  SR187_RS02925 (SR187_2975) - 583020..583781 (-) 762 WP_024532083.1 amino acid ABC transporter ATP-binding protein -
  SR187_RS02930 (SR187_2980) micA 583976..584680 (+) 705 WP_120171458.1 response regulator YycF Regulator
  SR187_RS02935 (SR187_2985) micB 584673..586022 (+) 1350 WP_024532081.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SR187_RS02940 (SR187_2990) vicX 586029..586832 (+) 804 WP_024532080.1 MBL fold metallo-hydrolase Regulator
  SR187_RS02945 (SR187_2995) pbp2b 587055..589130 (+) 2076 WP_024532079.1 penicillin-binding protein PBP2B -
  SR187_RS02950 (SR187_3000) recR 589139..589735 (+) 597 WP_024532078.1 recombination mediator RecR -
  SR187_RS02955 (SR187_3005) - 589951..590997 (+) 1047 WP_120171459.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51069.15 Da        Isoelectric Point: 4.6687

>NTDB_id=69443 SR187_RS02935 WP_024532081.1 584673..586022(+) (micB) [Streptococcus ruminantium strain GUT-187]
MFNQLRYLITTAEFWFVGILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIDGNYADILDLRGSPEITDMANSLNDLSE
VIRLTHDHLEQEKTRLTSILSYMSDGVVATDRIGRVIMINDMAQKQLGLSGKKQEQYHLLEVLDLPDRYTLRDLFAQTPE
IIIEHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMIRMITDLLSLSRIDNQVGQVDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGRITFSMKTTDSQLIVSISDEGLGIPKTDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHRGFIWAKSEYGHGSTFTIVLPYSKDIALDDWDEASEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=69443 SR187_RS02935 WP_024532081.1 584673..586022(+) (micB) [Streptococcus ruminantium strain GUT-187]
ATGTTTAATCAATTACGGTATCTAATTACTACAGCAGAGTTTTGGTTTGTCGGAATTTTGATTGGTTTTCTGATTGCTTT
GACGGTTCTCTTGATTGAAAACTACCGAGATAATAAGCAAATCAAACAACTGAATCAAAAAGTTAATGCTCTCATTGATG
GAAATTATGCAGATATTTTAGATTTGAGAGGGAGTCCAGAAATTACTGATATGGCTAACTCTCTTAATGATTTGTCAGAA
GTTATTCGGCTGACTCATGATCATTTAGAGCAGGAAAAAACACGCTTGACTTCCATTCTTTCCTATATGAGTGATGGGGT
GGTTGCAACGGACAGGATTGGGCGAGTTATCATGATCAACGATATGGCCCAGAAGCAGTTGGGGTTATCGGGAAAAAAGC
AGGAACAGTACCATCTGCTAGAGGTGTTAGATTTACCAGATCGGTATACTCTCAGAGATTTGTTTGCTCAGACACCAGAG
ATTATTATTGAGCACACCAATGAAAATGAGGAATTTCTTACTCTTCGTGCCAATTTTGCTACCATTCGTAGCGAGAGCGG
CTTGATTTCAGGTCTAGTAGTCGTCTTGCACGATATGACCGAACAGGCCAAAGAAGAGCGAGAGCGGCGCTTATTCGTAT
CCAATGTCAGTCATGAATTGCGGACTCCTTTGACTTCTGTTAAGTCCTACTTAGAAGCCTTGGATGAAGGAGCTTTGACT
GAGTCGGTTGCCCCGAGTTTTGTCAAAGTATCCTTGGATGAAACCAATCGAATGATACGGATGATTACAGACTTGTTAAG
TCTCTCCCGAATCGACAATCAAGTTGGTCAGGTAGATGTGGAGCTGATCAATTTTACGGCTTTTGTAACCTTTATCCTCA
ACCGTTTTGACCAGATGAAAAATGCCGACTCTGATAAGGTTTACACCATTGTACGTGATTATCAGATTAGCCCAATTTGG
GTGGAGATTGATACTGATAAGATGACGCAAGTTTTAGATAATATCCTGAACAATGCTATCAAATACTCACCTGATGGTGG
TAGGATTACTTTTAGTATGAAAACGACAGACAGCCAGTTGATTGTGTCTATTTCCGATGAAGGTTTGGGGATTCCAAAGA
CAGACTTACCTAAGATTTTCGACCGTTTTTATCGGGTAGACAAGGCACGCTCAAGGGCACAAGGAGGCACTGGCTTAGGA
CTGGCCATTGCCAAAGAAATCATCAAGCAACACAGGGGCTTTATTTGGGCTAAGAGCGAGTATGGCCATGGTTCAACCTT
TACCATTGTCTTACCATATAGTAAGGACATTGCTCTTGACGATTGGGATGAAGCTTCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TLH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.037

97.105

0.67
  vicK Streptococcus mutans UA159

69.479

89.755

0.624

Multiple sequence alignment