Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   M9410_RS09005 Genome accession   NZ_CP097799
Coordinates   1918939..1920273 (-) Length   444 a.a.
NCBI ID   WP_005757388.1    Uniprot ID   -
Organism   Pasteurella multocida strain 39639     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1913939..1925273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9410_RS08980 (M9410_08980) secM 1915459..1915773 (-) 315 WP_010907080.1 secA translation cis-regulator SecM -
  M9410_RS08985 (M9410_08985) - 1915863..1916168 (+) 306 WP_005723691.1 DUF721 domain-containing protein -
  M9410_RS08990 (M9410_08990) - 1916215..1917120 (-) 906 WP_005757382.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  M9410_RS08995 (M9410_08995) aroB 1917124..1918212 (-) 1089 WP_005757383.1 3-dehydroquinate synthase -
  M9410_RS09000 (M9410_09000) aroK 1918229..1918756 (-) 528 WP_005717623.1 shikimate kinase AroK -
  M9410_RS09005 (M9410_09005) comE 1918939..1920273 (-) 1335 WP_005757388.1 type IV pilus secretin PilQ Machinery gene
  M9410_RS09010 (M9410_09010) - 1920283..1920645 (-) 363 WP_005757389.1 pilus assembly protein PilP -
  M9410_RS09015 (M9410_09015) - 1920648..1921172 (-) 525 WP_005757390.1 hypothetical protein -
  M9410_RS09020 (M9410_09020) - 1921172..1921687 (-) 516 WP_005757392.1 hypothetical protein -
  M9410_RS09025 (M9410_09025) - 1921727..1922500 (-) 774 WP_005757393.1 pilus assembly protein PilM -
  M9410_RS09030 (M9410_09030) - 1922636..1925197 (+) 2562 WP_005757394.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 49254.67 Da        Isoelectric Point: 8.0315

>NTDB_id=692692 M9410_RS09005 WP_005757388.1 1918939..1920273(-) (comE) [Pasteurella multocida strain 39639]
MWRAFRKISFVYFLCGVAYVGSSQAQDAEHFYLRLKQAPLVEMLQYLALQQHQDLLIDDHLEGTLSLQMKKTTFEKCLQS
IARMKQLELHQEGKSYYLTSPSGVAANDTHHPTSLMTSSIKLHFAKAAEVVKSLTSGQGSLLSVGGSLSFDERTNLLLIQ
DEPQSIQRIKALVAEMDKPIEQIAIEARIVTMTDESLQELGVRWGLFQATEQAHTIAGSLAANGFSNIENQLNVNFSTNS
APVGSIALQLAKINGRLLDLELTALEREKHIEIIASPRLLTTNKKSASIKQGTEIPYVMKRGKDKSESVEFREAVLGLDV
TPHISKDNTILLDLLITQNTLGAPVVYDKGEIVSIDKQEINTQVIAQDGETIVLGGVFHDTMTKGVNKVPLLGDLPLLKH
VFSQKTERHQKRELVIFVTPHIIKPSQGSPEQKTTRVKKSAKSR

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=692692 M9410_RS09005 WP_005757388.1 1918939..1920273(-) (comE) [Pasteurella multocida strain 39639]
ATGTGGCGAGCATTCAGAAAAATATCTTTTGTGTACTTTTTATGTGGGGTTGCTTATGTTGGAAGTAGTCAAGCACAAGA
CGCAGAACATTTTTATTTACGTTTAAAACAAGCGCCTTTAGTTGAAATGTTACAGTATTTAGCATTGCAACAACATCAGG
ATTTGTTAATCGATGATCATTTAGAGGGCACATTATCATTACAGATGAAAAAGACAACCTTTGAGAAATGTTTACAGTCG
ATTGCAAGAATGAAACAACTTGAGTTACATCAAGAAGGAAAATCCTATTATTTAACTTCCCCTTCAGGTGTTGCAGCAAA
CGATACTCATCATCCTACGTCATTGATGACATCTTCAATAAAATTGCATTTTGCCAAAGCGGCAGAGGTGGTGAAATCTT
TAACTTCAGGGCAGGGAAGTTTACTTTCTGTCGGGGGGAGTTTGAGTTTTGATGAGCGGACTAATTTACTGCTGATTCAG
GATGAACCGCAATCAATACAGCGTATTAAAGCATTAGTAGCAGAAATGGATAAACCCATTGAACAAATTGCGATCGAAGC
CAGAATTGTGACGATGACAGACGAAAGTTTGCAGGAACTTGGCGTAAGATGGGGGCTATTTCAAGCAACAGAACAGGCAC
ATACTATTGCTGGGAGTTTAGCTGCAAACGGCTTTTCAAATATAGAAAACCAATTAAATGTGAATTTCTCGACCAATAGT
GCACCAGTTGGTTCCATCGCCCTACAGTTGGCGAAAATAAATGGTCGATTATTAGACTTGGAATTAACTGCCTTGGAACG
AGAAAAGCATATTGAGATTATTGCGAGTCCTCGTTTATTAACAACGAATAAAAAAAGTGCCAGTATTAAACAAGGGACGG
AAATTCCTTATGTGATGAAACGGGGAAAAGATAAAAGCGAATCGGTGGAATTTCGAGAAGCTGTATTAGGTTTAGATGTG
ACACCGCATATCTCAAAAGACAACACGATTTTATTAGATTTATTGATTACACAAAATACATTAGGTGCACCGGTAGTGTA
TGATAAAGGCGAAATTGTTTCGATCGATAAACAGGAAATCAATACTCAAGTCATCGCTCAAGATGGTGAAACCATCGTTT
TAGGTGGGGTGTTTCATGATACGATGACAAAGGGAGTCAATAAAGTACCACTACTAGGGGATTTGCCTTTGCTTAAACAT
GTGTTTAGCCAGAAAACTGAACGTCATCAAAAGCGGGAATTAGTGATTTTTGTCACTCCTCATATTATCAAACCTAGCCA
AGGTTCGCCTGAACAAAAAACAACAAGAGTTAAAAAATCTGCAAAATCGAGGTGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(264-424)

Bacterial type II/III secretion system short domain (Secretin_N)

(119-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

62.037

97.297

0.604
  comE Haemophilus influenzae 86-028NP

61.343

97.297

0.597
  comE Glaesserella parasuis strain SC1401

48.961

97.523

0.477
  pilQ Vibrio campbellii strain DS40M4

39.524

94.595

0.374
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

39.806

92.793

0.369
  pilQ Vibrio cholerae strain A1552

39.806

92.793

0.369