Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   STO1_RS07400 Genome accession   NZ_AP018338
Coordinates   1449998..1450657 (+) Length   219 a.a.
NCBI ID   WP_096422655.1    Uniprot ID   A0A224A8Y2
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1444998..1455657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS07360 (STO1_014290) - 1446116..1446352 (+) 237 WP_000964741.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  STO1_RS07365 (STO1_014300) amaP 1446452..1447015 (+) 564 WP_049520414.1 alkaline shock response membrane anchor protein AmaP -
  STO1_RS07370 (STO1_014310) - 1447026..1447196 (+) 171 WP_000454669.1 DUF2273 domain-containing protein -
  STO1_RS07375 (STO1_014320) - 1447208..1447792 (+) 585 WP_000072931.1 Asp23/Gls24 family envelope stress response protein -
  STO1_RS07380 (STO1_014330) - 1447834..1448037 (+) 204 WP_000102421.1 CsbD family protein -
  STO1_RS07385 (STO1_014340) - 1448255..1448776 (-) 522 WP_172843649.1 hypothetical protein -
  STO1_RS07390 (STO1_014350) - 1448846..1449369 (-) 524 Protein_1439 thiol-disulfide isomerase -
  STO1_RS07395 (STO1_014360) - 1449473..1449928 (-) 456 WP_096422653.1 GNAT family N-acetyltransferase -
  STO1_RS07400 (STO1_014370) cclA/cilC 1449998..1450657 (+) 660 WP_096422655.1 prepilin peptidase Machinery gene
  STO1_RS07405 (STO1_014380) trpA 1450629..1451405 (-) 777 WP_096422657.1 tryptophan synthase subunit alpha -
  STO1_RS07410 (STO1_014390) trpB 1451398..1452621 (-) 1224 WP_096422659.1 tryptophan synthase subunit beta -
  STO1_RS07415 (STO1_014400) - 1452599..1453198 (-) 600 WP_096422661.1 phosphoribosylanthranilate isomerase -
  STO1_RS07420 (STO1_014410) trpC 1453185..1453952 (-) 768 WP_096422663.1 indole-3-glycerol phosphate synthase TrpC -
  STO1_RS07425 (STO1_014420) trpD 1453949..1454953 (-) 1005 WP_000658688.1 anthranilate phosphoribosyltransferase -
  STO1_RS07430 (STO1_014430) - 1454964..1455530 (-) 567 WP_000601900.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24900.21 Da        Isoelectric Point: 8.1621

>NTDB_id=69072 STO1_RS07400 WP_096422655.1 1449998..1450657(+) (cclA/cilC) [Streptococcus oralis subsp. tigurinus strain osk_001]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIQPASHCDSCQTRLRPLDLIPIISQVIGRFRCRYCKIRYPIWYALFELGLG
LLFLAWSWGWLSLGKVILITAGLTLGIYDFRHQEYPLLVWMTFHLILMACSGWNLVMVFFLVLGIMAHFIDIHMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLSLAVCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=69072 STO1_RS07400 WP_096422655.1 1449998..1450657(+) (cclA/cilC) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTCGGTTTAGTCATTGATCGTTTTCCTGAGCA
ATCCATTATCCAACCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGACCCTTAGATTTGATTCCGATTATCTCTC
AAGTAATTGGTCGCTTTCGCTGTCGCTACTGCAAGATTCGCTATCCTATTTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTAGCTTGGTCTTGGGGCTGGCTTTCCTTAGGTAAAGTCATCCTCATCACTGCTGGTTTGACCTTGGGAAT
CTATGACTTTCGCCATCAGGAGTATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTCATGGCCTGCTCTGGCTGGA
ATCTGGTTATGGTCTTCTTTCTTGTTCTCGGAATCATGGCTCATTTTATCGATATCCACATGGGAGCAGGGGATTTTCTC
TTTCTGGCTTCTTGTGCGCTCGTCTTTAGCGTGACAGAATTACTCATCTTGATCCAGTTTGCTTCTGCGACGGGAATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTCACTTGCTGTTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A224A8Y2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

89.954

100

0.9
  cclA/cilC Streptococcus pneumoniae TIGR4

89.041

100

0.89
  cclA/cilC Streptococcus pneumoniae Rx1

89.041

100

0.89
  cclA/cilC Streptococcus pneumoniae D39

89.041

100

0.89
  cclA/cilC Streptococcus pneumoniae R6

89.041

100

0.89
  cclA/cilC Streptococcus mitis NCTC 12261

88.128

100

0.881

Multiple sequence alignment