Detailed information NTG0690340

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: M8286_RS05720
• Genome accession: NZ_CP097577
• Coordinates: 1187492..1189729 (-)
• Length: 745 a.a.
• NCBI ID: WP_275600585.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 3112
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1182492..1194729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M8286_RS05690 (M8286_05735)	tmk	1182596..1183234 (-)	639	WP_029171336.1	dTMP kinase	-
M8286_RS05695 (M8286_05740)	-	1183409..1184275 (+)	867	WP_002935357.1	YitT family protein	-
M8286_RS05700 (M8286_05745)	-	1184313..1185584 (-)	1272	WP_275600583.1	toxic anion resistance protein	-
M8286_RS05705 (M8286_05750)	-	1185590..1186417 (-)	828	WP_275600584.1	hypothetical protein	-
M8286_RS05710 (M8286_05755)	-	1186511..1187167 (-)	657	WP_002935353.1	CBS domain-containing protein	-
M8286_RS05715 (M8286_05760)	-	1187305..1187475 (-)	171	Protein_1081	transposase	-
M8286_RS05720 (M8286_05765)	comEC/celB	1187492..1189729 (-)	2238	WP_275600585.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
M8286_RS05725 (M8286_05770)	-	1189713..1190375 (-)	663	WP_275600586.1	helix-hairpin-helix domain-containing protein	-
M8286_RS05730 (M8286_05775)	-	1190442..1191188 (-)	747	WP_024407568.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
M8286_RS05735 (M8286_05780)	-	1191600..1193045 (+)	1446	WP_275600587.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
M8286_RS05740 (M8286_05785)	-	1193197..1193982 (+)	786	WP_024385481.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83809.77 Da
• Isoelectric Point: 7.3713

>NTDB_id=690340 M8286_RS05720 WP_275600585.1 1187492..1189729(-) (comEC/celB) [Streptococcus suis strain 3112]
MSRSIKLPYQPIHLAVLAVAAYFAVHSFFLLTMGLLSLLLVVFGFRQGKVVFLKTLPLLVLCGLFFGCQKVQWERAAQLA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQTYQVFYKLASQEEQAYFQKLTGLVQLEVEAEVSLPAGQRNFNGFDYQAYL
KTQGIYRTVTMTKIKQISPVQSWNIFDWLSSWRRSALVSIKTNFPAPMSHYMTGLLFGDLDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQVPFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVMVFVCLLML
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPLVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSGLVLLLLLVSLFMLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVEFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HVGDVLEVAKQVQIGQIYVSPGSLTVPDFVATLKEINVPVEVVAVGDRLPIFDSNLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIKAYPNLPVDVLKAGHHGSQGSSYPAFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=690340 M8286_RS05720 WP_275600585.1 1187492..1189729(-) (comEC/celB) [Streptococcus suis strain 3112]
ATGTCACGGTCGATTAAGCTCCCCTACCAGCCCATTCACCTGGCAGTCTTGGCGGTGGCGGCCTACTTTGCAGTCCATTC
TTTTTTCCTCTTGACAATGGGCCTGCTAAGTCTGTTACTAGTTGTCTTTGGGTTTCGGCAAGGTAAGGTAGTTTTCCTCA
AAACGCTACCGCTTCTAGTTCTGTGTGGTCTCTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGCCCAGTTAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCCTGTCTTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGCTGACAGGTCTGG
TCCAGCTAGAAGTGGAAGCAGAAGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAACGGCTTTGACTATCAAGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCACAATGACAAAGATAAAACAGATTTCCCCTGTCCAGTCTTGGAATATTTTTGA
CTGGCTATCAAGCTGGCGGAGAAGCGCACTCGTTTCTATCAAAACCAATTTTCCAGCACCGATGAGTCATTATATGACAG
GGCTCTTGTTTGGGGATCTGGATAGTGAGTTTGACCAGATGAGCGACCTCTATTCTAGTCTAGGTATCATTCATCTTTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATAGACAAGTTTCGTTGGATTTTGTTGCGGTTGGGCTTGACAAAGGAAAC
GGTGGATAAGTTGCAGGTTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCGGTGTCAGTGGTGCGGTCCCTGG
TCCAAAAAATTCTGGGCAATATGGGCTTGCGGAAGTTGGATAATTTTGCGGTGATGGTCTTTGTCTGCCTGCTGATGCTG
CCCCGATTTTTATTGACGGCAGGAGGAGTGTTGACCTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTTAGTATTTCTCTTGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTCCAGCCTCTGTCCATTCTCTTGACATTTGTTTTTTCCTTTATCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCCTGTCACCTCTGGTCAAGATAACTTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGTAAGCCGTCTGGGCTGGTTCTCTTGCTTTTGCTGGTCAGCCTCTTCA
TGCTTTACGATTTTCACAGGAAGAAAAAATGGCTCTTAGGACTGAGCCTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CATCCTCTGGAAAATGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGACGGGTCGAGTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACCTTGATACCTTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCATACCGACGCTGAC
CATGTGGGCGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGACAGATTTACGTGTCGCCAGGAAGTCTGACGGTGCC
TGACTTTGTAGCCACCTTGAAAGAAATCAATGTCCCTGTTGAAGTGGTGGCGGTAGGCGACCGCTTACCGATTTTTGACT
CCAATCTGGAAGTCCTCTATCCAGACGGGACGGGTGACGGTGGCAATAATGATTCTATTGTCCTTTACGGTCGTTTGTTG
GAAACCAATTTTCTCTTTACAGGGGATTTGGAACAGGGGGAATTGGACTTGATAAAAGCCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCTGGTCACCACGGCTCTCAAGGCTCTTCCTATCCAGCATTTTTAGACCATATCGGAGCCAAGATTGCCC
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCACCCTCACCAAGAAACTTTGGATCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACGGACCAGCAAGGAGCTATTCGTTTCCGAGGCTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-460)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.631	100	0.546
comEC/celB	Streptococcus mitis NCTC 12261	53.504	99.597	0.533
comEC/celB	Streptococcus pneumoniae TIGR4	52.624	99.732	0.525
comEC/celB	Streptococcus pneumoniae Rx1	52.624	99.732	0.525
comEC/celB	Streptococcus pneumoniae D39	52.624	99.732	0.525
comEC/celB	Streptococcus pneumoniae R6	52.624	99.732	0.525
comEC	Lactococcus lactis subsp. cremoris KW2	48.663	100	0.489