Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   M8286_RS04105 Genome accession   NZ_CP097577
Coordinates   834280..835659 (+) Length   459 a.a.
NCBI ID   WP_275601569.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 829280..840659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS04075 (M8286_04100) pstA 829633..830520 (+) 888 WP_358639239.1 phosphate ABC transporter permease PstA -
  M8286_RS04080 (M8286_04105) pstB 830545..831348 (+) 804 WP_275601566.1 phosphate ABC transporter ATP-binding protein PstB -
  M8286_RS04085 (M8286_04110) pstB 831360..832118 (+) 759 WP_275601567.1 phosphate ABC transporter ATP-binding protein PstB -
  M8286_RS04090 (M8286_04115) phoU 832147..832803 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  M8286_RS04095 (M8286_04120) - 832969..833415 (+) 447 WP_275601568.1 hypothetical protein -
  M8286_RS04100 (M8286_04125) ciaR 833616..834287 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  M8286_RS04105 (M8286_04130) ciaH 834280..835659 (+) 1380 WP_275601569.1 HAMP domain-containing sensor histidine kinase Regulator
  M8286_RS04110 (M8286_04135) - 835760..836989 (+) 1230 WP_275601570.1 transglutaminase domain-containing protein -
  M8286_RS04115 (M8286_04140) rpsT 837256..837504 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  M8286_RS04120 (M8286_04145) coaA 837563..838483 (-) 921 WP_002935283.1 type I pantothenate kinase -
  M8286_RS04125 (M8286_04150) - 838592..839182 (+) 591 WP_014635990.1 class I SAM-dependent methyltransferase -
  M8286_RS04130 (M8286_04155) - 839179..840456 (+) 1278 WP_275601571.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51869.55 Da        Isoelectric Point: 8.7379

>NTDB_id=690337 M8286_RS04105 WP_275601569.1 834280..835659(+) (ciaH) [Streptococcus suis strain 3112]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLTTDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=690337 M8286_RS04105 WP_275601569.1 834280..835659(+) (ciaH) [Streptococcus suis strain 3112]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACTTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACGACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGACTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATCAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGTATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTAGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGTGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae D39

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae R6

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.345

99.782

0.492
  ciaH Streptococcus mutans UA159

49.451

99.129

0.49