Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   OTU47_RS05100 Genome accession   NZ_CP113115
Coordinates   942941..943600 (-) Length   219 a.a.
NCBI ID   WP_000565003.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP2     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 937941..948600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTU47_RS05070 (OTU47_05070) - 938121..938720 (+) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -
  OTU47_RS05075 (OTU47_05075) trpB 938698..939921 (+) 1224 WP_000331289.1 tryptophan synthase subunit beta -
  OTU47_RS05080 (OTU47_05080) trpA 939914..940690 (+) 777 WP_001127027.1 tryptophan synthase subunit alpha -
  OTU47_RS05085 (OTU47_05085) - 940662..940772 (-) 111 Protein_951 prepilin peptidase -
  OTU47_RS05090 (OTU47_05090) - 940992..941723 (+) 732 WP_000934017.1 hypothetical protein -
  OTU47_RS05095 (OTU47_05095) - 941738..942889 (+) 1152 WP_000481750.1 helix-turn-helix domain-containing protein -
  OTU47_RS05100 (OTU47_05100) cclA/cilC 942941..943600 (-) 660 WP_000565003.1 prepilin peptidase Machinery gene
  OTU47_RS05105 (OTU47_05105) - 943670..944116 (+) 447 WP_000155414.1 GNAT family N-acetyltransferase -
  OTU47_RS05110 (OTU47_05110) - 944344..945522 (-) 1179 WP_000175876.1 ROK family transcriptional regulator -
  OTU47_RS05115 (OTU47_05115) - 945802..947064 (+) 1263 WP_000413339.1 PTS sugar transporter subunit IIC -
  OTU47_RS05120 (OTU47_05120) - 947067..947963 (+) 897 WP_050118010.1 PEP phosphonomutase -
  OTU47_RS05125 (OTU47_05125) - 947978..948295 (+) 318 WP_267747168.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24841.94 Da        Isoelectric Point: 7.6166

>NTDB_id=689804 OTU47_RS05100 WP_000565003.1 942941..943600(-) (cclA/cilC) [Streptococcus pneumoniae strain NP2]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=689804 OTU47_RS05100 WP_000565003.1 942941..943600(-) (cclA/cilC) [Streptococcus pneumoniae strain NP2]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCATAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
AGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae Rx1

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae D39

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae R6

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868