Detailed information NTG0068965

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: HT085_RS04250
• Genome accession: NZ_AP023069
• Coordinates: 826142..827173 (-)
• Length: 343 a.a.
• NCBI ID: WP_003691202.1
• Uniprot ID: Q5F8L2
• Organism: Neisseria gonorrhoeae strain TUM19854
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 821142..832173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HT085_RS04225 (TUM19854C_08130)	-	822356..822970 (+)	615	WP_003691204.1	molybdenum cofactor guanylyltransferase	-
HT085_RS04230 (TUM19854C_08140)	-	823133..823750 (+)	618	WP_010358100.1	riboflavin synthase	-
HT085_RS04235 (TUM19854C_08150)	-	823758..824621 (+)	864	WP_003688678.1	ATP-binding protein	-
HT085_RS04240 (TUM19854C_08160)	-	824634..825068 (-)	435	WP_003688677.1	Spy/CpxP family protein refolding chaperone	-
HT085_RS04245 (TUM19854C_08170)	rpe	825214..825897 (+)	684	WP_003688675.1	ribulose-phosphate 3-epimerase	-
HT085_RS04250 (TUM19854C_08180)	ruvB	826142..827173 (-)	1032	WP_003691202.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
HT085_RS04255 (TUM19854C_08190)	-	827255..827563 (-)	309	WP_002232489.1	hypothetical protein	-
HT085_RS04260 (TUM19854C_08200)	-	827982..829214 (-)	1233	WP_003691200.1	multifunctional CCA addition/repair protein	-
HT085_RS04265 (TUM19854C_08210)	-	829293..830921 (-)	1629	WP_010951119.1	ABC-F family ATPase	-
HT085_RS04270 (TUM19854C_08220)	-	831071..831445 (+)	375	WP_003688664.1	arsenate reductase	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37638.23 Da
• Isoelectric Point: 5.4704

>NTDB_id=68965 HT085_RS04250 WP_003691202.1 826142..827173(-) (ruvB) [Neisseria gonorrhoeae strain TUM19854]
MLQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQHKAKEQLAIFIQAAKKRGEALDHVLLFGPPGLGKTTL
AHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFIDEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKID
LPPFTLVGATTRAGMLTNPLRDRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMGEEGAMEVAKRSRGTPRIANRLLRRVR
DFADVKNNGVIDAAVADAALSMLDVDAQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGESTDTIEDVIEPYLIQQGFL
QRTPRGRMATERAYLHFGLPVEK

Nucleotide

• Length: 1032 bp

>NTDB_id=68965 HT085_RS04250 WP_003691202.1 826142..827173(-) (ruvB) [Neisseria gonorrhoeae strain TUM19854]
ATGCTGCAAACCGACAACCTGACCGCCGCGCAACCGCAACGCATCGTTGCCGCCCAAACCGCCTCCGCACAGGAAGAACT
GCTCGAACGCGCCCTCCGCCCCAAAACGCTGGACGACTACATCGGGCAGCATAAAGCCAAAGAGCAGCTCGCCATCTTCA
TCCAAGCCGCCAAAAAACGCGGCGAAGCACTCGACCACGTCCTGCTTTTCGGCCCGCCCGGACTGGGCAAAACCACCCTT
GCCCACATCATCGCCAAAGAGTTGGGCGTAAATTTGCGCCAAACCAGCGGCCCCGTCCTCGAACGCGCCGGCGACCTCGC
CGCCCTTTTGACCAACCTTGATCCGCACGACGTATTGTTTATCGACGAAATCCACCGGCTAAGCCCCGTCGTCGAGGAAA
TCCTCTATCCCGCGCTCGAAGACTACCGGCTCGACATTATGATAGGCGAAGGACCCGCCGCACGTTCCGTCAAAATCGAC
CTGCCGCCCTTCACCCTCGTCGGCGCGACCACCCGCGCCGGTATGCTGACCAACCCGTTGCGCGACCGCTTCGGCATCGT
CTCCCGCCTCGAGTTTTACGAAAACCGCGACCTTACCACCATCGTCAGCCGTTCGGCACAACTGTTGCAGCTCGATATGG
GCGAAGAAGGCGCGATGGAAGTCGCCAAACGCAGCCGCGGCACGCCCCGCATCGCCAACCGCCTGTTGCGCCGCGTGCGC
GATTTCGCCGACGTGAAAAACAACGGCGTAATCGATGCCGCCGTCGCCGATGCCGCTTTAAGTATGCTGGACGTGGACGC
GCAGGGGCTGGACGTGATGGACAGGAAATTCCTCGAAGCCGTTTTGCACAAATTCGGCGGCGGCCCCGTCGGTTTGGACA
ACGTTGCCGCCGCCATCGGCGAATCTACGGACACCATCGAAGACGTTATCGAACCCTACCTCATCCAACAAGGCTTTTTG
CAACGCACCCCGCGCGGCAGGATGGCGACCGAACGCGCCTACCTGCATTTCGGGCTGCCCGTCGAAAAATAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (268-337)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (32-190)

• RuvB AAA lid domain (AAA_lid_4) (193-266)

3D structure

• AlphaFold DB: Q5F8L2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.55	95.335	0.577
ruvB	Streptococcus pneumoniae TIGR4	62.739	91.545	0.574
ruvB	Streptococcus pneumoniae R6	62.739	91.545	0.574
ruvB	Streptococcus pneumoniae D39	62.739	91.545	0.574
ruvB	Synechocystis sp. PCC 6803	54.268	95.627	0.519
ruvB	Helicobacter pylori 26695	56.55	91.254	0.516