Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   M3706_RS01015 Genome accession   NZ_CP097337
Coordinates   199952..200290 (-) Length   112 a.a.
NCBI ID   WP_006251644.1    Uniprot ID   A0A248ZWT2
Organism   Mannheimia haemolytica strain NCTC 9712     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 194952..205290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M3706_RS01000 (M3706_01000) - 194954..196423 (-) 1470 WP_006251642.1 class I SAM-dependent DNA methyltransferase -
  M3706_RS01005 (M3706_01005) - 196471..198822 (-) 2352 WP_006250003.1 DEAD/DEAH box helicase family protein -
  M3706_RS01010 (M3706_01010) asd 198894..199787 (-) 894 WP_006251643.1 archaetidylserine decarboxylase -
  M3706_RS01015 (M3706_01015) comEA/comE1 199952..200290 (-) 339 WP_006251644.1 ComEA family DNA-binding protein Machinery gene
  M3706_RS01020 (M3706_01020) - 200583..201902 (+) 1320 WP_006251645.1 LysM-like peptidoglycan-binding domain-containing protein -
  M3706_RS01025 (M3706_01025) - 201962..202378 (+) 417 WP_020824267.1 MliC family protein -
  M3706_RS01030 (M3706_01030) waaF 202489..203526 (+) 1038 WP_020824266.1 lipopolysaccharide heptosyltransferase II -
  M3706_RS01035 (M3706_01035) rfaC 203594..204553 (+) 960 WP_006250332.1 lipopolysaccharide heptosyltransferase RfaC -
  M3706_RS01040 (M3706_01040) rpsL 204674..205048 (+) 375 WP_005543325.1 30S ribosomal protein S12 -

Sequence

Protein


Download         Length: 112 a.a.        Molecular weight: 12111.91 Da        Isoelectric Point: 10.0993

>NTDB_id=688708 M3706_RS01015 WP_006251644.1 199952..200290(-) (comEA/comE1) [Mannheimia haemolytica strain NCTC 9712]
MKKIKQLGLTFLFGLNAMAFAQTPPTTMPVEQNAVTQPVQQTQITNANAVNINTASAAELQDKLVGIGQKKAQAIVDYRT
KNGNFKNIEQLAEVSGIGQATVEKNRANIILE

Nucleotide


Download         Length: 339 bp        

>NTDB_id=688708 M3706_RS01015 WP_006251644.1 199952..200290(-) (comEA/comE1) [Mannheimia haemolytica strain NCTC 9712]
ATGAAGAAAATCAAACAACTTGGTCTAACATTCTTGTTTGGCTTAAATGCAATGGCTTTTGCCCAAACACCGCCAACTAC
AATGCCTGTTGAACAAAATGCAGTCACTCAACCCGTACAGCAAACACAAATCACCAACGCCAATGCGGTAAATATCAATA
CTGCTAGTGCTGCTGAATTGCAAGACAAGCTAGTGGGAATTGGGCAGAAAAAAGCTCAAGCGATTGTCGATTACCGTACT
AAAAACGGCAATTTTAAAAACATTGAGCAACTTGCTGAAGTCTCCGGAATTGGGCAAGCAACGGTAGAAAAAAATCGAGC
CAATATTATTTTAGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(46-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A248ZWT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

59.292

100

0.598
  comE1/comEA Haemophilus influenzae Rd KW20

52.747

81.25

0.429
  comEA Vibrio cholerae C6706

54.651

76.786

0.42
  comEA Vibrio cholerae strain A1552

54.651

76.786

0.42