Detailed information NTG0684212

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: MZK36_RS05735
• Genome accession: NZ_CP096809
• Coordinates: 1145511..1146464 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain SP007
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1140511..1151464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MZK36_RS05710 (MZK36_05675)	-	1140992..1141087 (-)	96	Protein_1133	IS630 family transposase	-
MZK36_RS05715 (MZK36_05680)	-	1141500..1141841 (+)	342	Protein_1134	transposase	-
MZK36_RS05720 (MZK36_05685)	prsA	1141958..1142899 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
MZK36_RS05725 (MZK36_05690)	-	1142966..1143679 (-)	714	WP_000230400.1	O-methyltransferase	-
MZK36_RS05730 (MZK36_05695)	pepF	1143681..1145492 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
MZK36_RS05735 (MZK36_05700)	coiA	1145511..1146464 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
MZK36_RS05740 (MZK36_05705)	tehB	1146537..1147397 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
MZK36_RS05745 (MZK36_05710)	smpB	1147413..1147880 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
MZK36_RS05750 (MZK36_05715)	rnr	1147843..1150197 (-)	2355	WP_000654886.1	ribonuclease R	-
MZK36_RS05755 (MZK36_05720)	secG	1150299..1150532 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
MZK36_RS05760 (MZK36_05725)	rpmG	1150572..1150721 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=684212 MZK36_RS05735 WP_000495909.1 1145511..1146464(-) (coiA) [Streptococcus pneumoniae strain SP007]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=684212 MZK36_RS05735 WP_000495909.1 1145511..1146464(-) (coiA) [Streptococcus pneumoniae strain SP007]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435