Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SNAG_RS06105 Genome accession   NZ_AP017652
Coordinates   1176202..1177539 (-) Length   445 a.a.
NCBI ID   WP_096407550.1    Uniprot ID   A0A1E1GBC1
Organism   Streptococcus sp. NPS 308     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1171202..1182539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS06080 (SNAG_1190) rpiA 1171873..1172556 (-) 684 WP_096407539.1 ribose-5-phosphate isomerase RpiA -
  SNAG_RS06085 (SNAG_1191) - 1172662..1173591 (-) 930 WP_096407542.1 peptidase U32 family protein -
  SNAG_RS06090 (SNAG_1192) - 1173718..1174398 (-) 681 WP_096407544.1 ABC transporter ATP-binding protein -
  SNAG_RS06095 (SNAG_1193) - 1174412..1175467 (-) 1056 WP_096407546.1 ABC transporter permease -
  SNAG_RS06100 (SNAG_1194) - 1175853..1176137 (+) 285 WP_096407548.1 DUF3270 domain-containing protein -
  SNAG_RS06105 (SNAG_1195) ciaH 1176202..1177539 (-) 1338 WP_096407550.1 HAMP domain-containing sensor histidine kinase Regulator
  SNAG_RS06110 (SNAG_1196) ciaR 1177529..1178203 (-) 675 WP_061453486.1 two-component system response regulator CiaR Regulator
  SNAG_RS06115 (SNAG_1197) - 1178314..1180860 (-) 2547 WP_096407552.1 M1 family metallopeptidase -
  SNAG_RS06120 (SNAG_1198) - 1180982..1181422 (-) 441 WP_096408864.1 ASCH domain-containing protein -
  SNAG_RS06125 - 1181478..1181738 (-) 261 WP_231906657.1 hypothetical protein -
  SNAG_RS06130 (SNAG_1199) - 1181857..1182411 (-) 555 WP_096407556.1 DUF4304 domain-containing protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 50915.61 Da        Isoelectric Point: 9.6326

>NTDB_id=68353 SNAG_RS06105 WP_096407550.1 1176202..1177539(-) (ciaH) [Streptococcus sp. NPS 308]
MFNKLKKTWYADDFSYFIRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLQALSSSPQAVIQLALNRATEEVKDIQTAT
ADASKAEIKPNVSSNTEVLLFDKDFNQLLLGNRFLGLDKIKLDKKELNHIRQIQVFNSYGQEETYRMVLMETNSSTVSSN
VKYAAVLINTSQLEQISQNHEHLIVVVMASFWLLSLIASVYLARVSVKPLLESMQKQKSFVENASHELRTPLAVLQNRLE
NLFRKPEATIMESSESIASSLEEVRNMRFLTTNLLNLARRDDGIKPEIAEVSPQFFKTTFANYELIAYENDRVFNYENRI
YRPFMTDQLLLKQLMTILFDNAIKYTEEDGKIEFVVYATDRHLYLTVTDNGIGISAADKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALRGTISVKDNKPRGTIFEVKIAIQSPSKRKNK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=68353 SNAG_RS06105 WP_096407550.1 1176202..1177539(-) (ciaH) [Streptococcus sp. NPS 308]
ATGTTCAATAAATTAAAAAAAACATGGTACGCAGATGATTTCAGCTATTTCATTCGAAATTTCGGAGTGTTCACCTTGAT
TTTCTCTGCTATGACCTTGATTATCCTTCAGGTCATGCACTCGAGTCTCTATACTTCTGTAGATGAAAAACTACAAGCCC
TTAGTAGTAGTCCTCAAGCGGTCATTCAGTTAGCCCTGAATCGGGCAACTGAGGAAGTCAAGGATATTCAAACAGCAACA
GCGGATGCCAGCAAGGCTGAAATCAAGCCCAATGTTAGCTCCAATACAGAAGTTTTGCTTTTTGACAAGGATTTTAACCA
ACTCTTACTGGGCAATCGCTTTTTAGGCTTGGACAAGATCAAACTGGACAAGAAAGAGTTGAATCATATTCGGCAAATCC
AAGTTTTCAACAGCTATGGTCAGGAAGAAACCTATCGAATGGTCTTGATGGAAACCAACTCTTCCACCGTATCAAGTAAT
GTCAAATATGCGGCGGTTCTAATCAATACCAGCCAGCTTGAGCAAATCAGCCAAAATCACGAGCATTTAATTGTTGTAGT
CATGGCTAGTTTCTGGCTCCTGTCTTTAATTGCCAGTGTTTACCTGGCACGTGTCAGTGTCAAACCCTTGCTGGAAAGCA
TGCAAAAGCAGAAGTCCTTTGTTGAAAATGCTAGTCACGAACTGAGAACGCCTTTAGCCGTTTTACAAAATCGCTTAGAG
AATCTCTTTCGAAAACCAGAGGCAACCATCATGGAATCCAGCGAAAGTATTGCTTCCAGTCTTGAAGAAGTTCGCAACAT
GCGTTTCCTTACGACCAATCTTCTCAACCTTGCACGTCGAGATGATGGAATCAAACCAGAAATAGCAGAAGTTTCTCCAC
AATTCTTTAAAACAACCTTTGCCAACTATGAGTTGATTGCCTATGAAAATGATCGTGTTTTCAACTATGAAAATCGAATT
TATCGTCCATTCATGACCGATCAGTTGCTCCTAAAACAACTCATGACCATTTTATTTGACAATGCCATCAAGTATACCGA
AGAAGATGGGAAAATTGAGTTTGTAGTCTATGCTACAGATCGCCACCTCTATCTTACAGTAACGGATAACGGAATTGGAA
TTTCAGCTGCTGACAAGAAGAAAATCTTTGACCGATTTTACCGTGTAGACAAGGCAAGAACTCGTCAGAAAGGTGGCTTT
GGTTTGGGACTTTCTTTGGCTAAGCAGATTGTTGATGCCTTACGAGGAACGATTAGCGTAAAAGATAACAAACCTAGAGG
AACAATTTTTGAAGTTAAGATTGCTATTCAATCTCCTTCAAAACGAAAGAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-283)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1GBC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

83.973

99.551

0.836
  ciaH Streptococcus pneumoniae D39

83.973

99.551

0.836
  ciaH Streptococcus pneumoniae R6

83.973

99.551

0.836
  ciaH Streptococcus pneumoniae TIGR4

83.973

99.551

0.836
  ciaH Streptococcus mutans UA159

55.251

98.427

0.544

Multiple sequence alignment