Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SNAG_RS02455 Genome accession   NZ_AP017652
Coordinates   438799..439458 (-) Length   219 a.a.
NCBI ID   WP_096406220.1    Uniprot ID   A0A1E1G9G6
Organism   Streptococcus sp. NPS 308     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 433799..444458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SNAG_RS02425 (SNAG_0482) - 433926..434492 (+) 567 WP_096406205.1 aminodeoxychorismate/anthranilate synthase component II -
  SNAG_RS02430 (SNAG_0483) trpD 434503..435507 (+) 1005 WP_096406207.1 anthranilate phosphoribosyltransferase -
  SNAG_RS02435 (SNAG_0484) trpC 435504..436271 (+) 768 WP_096406210.1 indole-3-glycerol phosphate synthase TrpC -
  SNAG_RS02440 (SNAG_0485) - 436258..436857 (+) 600 WP_172842379.1 phosphoribosylanthranilate isomerase -
  SNAG_RS02445 (SNAG_0486) trpB 436835..438058 (+) 1224 WP_096406215.1 tryptophan synthase subunit beta -
  SNAG_RS02450 (SNAG_0487) trpA 438051..438827 (+) 777 WP_096406217.1 tryptophan synthase subunit alpha -
  SNAG_RS02455 (SNAG_0488) cclA/cilC 438799..439458 (-) 660 WP_096406220.1 A24 family peptidase Machinery gene
  SNAG_RS02460 (SNAG_0489) - 439528..439983 (+) 456 WP_096406222.1 GNAT family N-acetyltransferase -
  SNAG_RS10000 - 440086..440608 (+) 523 Protein_427 thiol-disulfide isomerase -
  SNAG_RS02475 (SNAG_0491) - 440805..441200 (+) 396 WP_231906652.1 hypothetical protein -
  SNAG_RS02480 (SNAG_0492) - 441419..441622 (-) 204 WP_000102421.1 CsbD family protein -
  SNAG_RS02485 (SNAG_0493) - 441664..442248 (-) 585 WP_070696162.1 Asp23/Gls24 family envelope stress response protein -
  SNAG_RS02490 (SNAG_0494) - 442260..442430 (-) 171 WP_000454669.1 DUF2273 domain-containing protein -
  SNAG_RS02495 (SNAG_0495) amaP 442441..443004 (-) 564 WP_025168468.1 alkaline shock response membrane anchor protein AmaP -
  SNAG_RS02500 (SNAG_0496) - 443104..443340 (-) 237 WP_000964741.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24973.31 Da        Isoelectric Point: 8.1576

>NTDB_id=68339 SNAG_RS02455 WP_096406220.1 438799..439458(-) (cclA/cilC) [Streptococcus sp. NPS 308]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTRLRPLDLIPIISQLIGRFRCRYCKVRYPVWYALFELGLG
ILFLAWSWGWLSLGQVILITAGLTLGIYDFRHQEYPLLVWMTFHLVLMACSDWNLVMIFFLALGIIAHFIDIRMGAGDFL
FLASCALVFSVIELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACMIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=68339 SNAG_RS02455 WP_096406220.1 438799..439458(-) (cclA/cilC) [Streptococcus sp. NPS 308]
ATGATTGATCTTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTCGGTTTGGTCATTGACCGTTTCCCTGAGCA
ATCCATTATTCGACCAGCTAGCCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTATCTCTC
AATTGATTGGTCGCTTTCGCTGTCGCTACTGCAAGGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
ATCCTCTTTCTAGCTTGGTCTTGGGGCTGGCTTTCCTTGGGTCAAGTCATCCTGATCACTGCTGGCTTGACCTTGGGTAT
CTATGACTTTCGCCATCAGGAGTATCCCTTACTGGTCTGGATGACTTTCCATCTAGTCCTAATGGCCTGCTCTGACTGGA
ATCTGGTTATGATTTTCTTCCTTGCCCTTGGAATCATAGCCCATTTTATCGATATCCGCATGGGAGCAGGGGATTTTCTA
TTTCTGGCTTCTTGTGCTCTCGTCTTTAGTGTGATAGAGTTGCTGATCTTGATTCAGTTTGCTTCTGCGACGGGGATCCT
AGCCTTTCTCCTCCAAAAGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTCTTGCTAGCTGCTTGTATGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E1G9G6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

89.498

100

0.895
  cclA/cilC Streptococcus pneumoniae Rx1

89.041

100

0.89
  cclA/cilC Streptococcus pneumoniae D39

89.041

100

0.89
  cclA/cilC Streptococcus pneumoniae R6

89.041

100

0.89
  cclA/cilC Streptococcus mitis NCTC 12261

88.128

100

0.881
  cclA/cilC Streptococcus pneumoniae TIGR4

88.128

100

0.881

Multiple sequence alignment