Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   MU520_RS05375 Genome accession   NZ_CP095463
Coordinates   1089936..1091315 (+) Length   459 a.a.
NCBI ID   WP_024409447.1    Uniprot ID   -
Organism   Streptococcus suis strain TJS56     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1084936..1096315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MU520_RS05345 pstA 1085395..1086282 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  MU520_RS05350 pstB 1086307..1087110 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  MU520_RS05355 pstB 1087122..1087880 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  MU520_RS05360 phoU 1087909..1088565 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  MU520_RS05365 - 1088731..1089078 (+) 348 WP_014635995.1 hypothetical protein -
  MU520_RS05370 ciaR 1089272..1089943 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  MU520_RS05375 ciaH 1089936..1091315 (+) 1380 WP_024409447.1 HAMP domain-containing sensor histidine kinase Regulator
  MU520_RS05380 - 1091416..1092645 (+) 1230 WP_014637854.1 transglutaminase domain-containing protein -
  MU520_RS05385 rpsT 1092908..1093156 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  MU520_RS05390 coaA 1093215..1094135 (-) 921 WP_002935283.1 type I pantothenate kinase -
  MU520_RS05395 - 1094244..1094834 (+) 591 WP_014637855.1 class I SAM-dependent methyltransferase -
  MU520_RS05400 - 1094831..1096108 (+) 1278 WP_014637856.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51827.45 Da        Isoelectric Point: 6.5295

>NTDB_id=677009 MU520_RS05375 WP_024409447.1 1089936..1091315(+) (ciaH) [Streptococcus suis strain TJS56]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=677009 MU520_RS05375 WP_024409447.1 1089936..1091315(+) (ciaH) [Streptococcus suis strain TJS56]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGCTATCAAAAACAA
AAGGACTTTGTCGAAAATGCTAGTCATGAGTTGCGTACGCCGCTGGCTGTTCTCCAAAATCGTTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAGAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTCACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACACGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGTTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae D39

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae R6

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae TIGR4

49.563

99.782

0.495
  ciaH Streptococcus mutans UA159

50.112

97.386

0.488