Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MP619_RS02570 Genome accession   NZ_CP095081
Coordinates   477321..478007 (+) Length   228 a.a.
NCBI ID   WP_268227847.1    Uniprot ID   A0AAE9UMP3
Organism   Streptococcus dysgalactiae strain WJ001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 472321..483007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS02545 (MP619_02535) ktrB 472429..473805 (-) 1377 WP_129555318.1 potassium uptake transporter channel subunit KtrB -
  MP619_RS02550 (MP619_02540) rsmG 473889..474602 (-) 714 WP_129555319.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  MP619_RS02555 (MP619_02545) - 474755..475312 (+) 558 WP_129555320.1 LemA family protein -
  MP619_RS02560 (MP619_02550) htpX 475357..476250 (+) 894 WP_129555321.1 zinc metalloprotease HtpX -
  MP619_RS02565 (MP619_02555) - 476517..477050 (+) 534 WP_129555322.1 DUF177 domain-containing protein -
  MP619_RS02570 (MP619_02560) covR 477321..478007 (+) 687 WP_268227847.1 two-component system response regulator CovR Regulator
  MP619_RS02575 (MP619_02565) - 478013..479512 (+) 1500 WP_155782822.1 HAMP domain-containing histidine kinase -
  MP619_RS02580 (MP619_02570) nrdR 479717..480211 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  MP619_RS02585 (MP619_02575) - 480195..481373 (+) 1179 WP_129555324.1 DnaD domain protein -
  MP619_RS02590 (MP619_02580) dnaI 481374..482276 (+) 903 WP_003058998.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26581.63 Da        Isoelectric Point: 4.7246

>NTDB_id=675086 MP619_RS02570 WP_268227847.1 477321..478007(+) (covR) [Streptococcus dysgalactiae strain WJ001]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLKPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=675086 MP619_RS02570 WP_268227847.1 477321..478007(+) (covR) [Streptococcus dysgalactiae strain WJ001]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
CGAAGTAACTGTTGAAGTGAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGACTTTGACTTGATTCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACCGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGGTTAGACCGTGGTGCGGATGATTACATTGTGAAGCCATTTGCAATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAAACCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACCAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425