Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   MP619_RS00355 Genome accession   NZ_CP095081
Coordinates   56705..57616 (+) Length   303 a.a.
NCBI ID   WP_129555155.1    Uniprot ID   A0A9X7S0S3
Organism   Streptococcus dysgalactiae strain WJ001     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 51705..62616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS00335 (MP619_00330) purE 52721..53209 (+) 489 WP_129555152.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  MP619_RS00340 (MP619_00335) purK 53196..54269 (+) 1074 WP_129555153.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  MP619_RS00345 (MP619_00340) - 54280..55008 (+) 729 WP_129555154.1 hypothetical protein -
  MP619_RS00350 (MP619_00345) purB 55270..56562 (+) 1293 WP_022554088.1 adenylosuccinate lyase -
  MP619_RS00355 (MP619_00350) comR 56705..57616 (+) 912 WP_129555155.1 XRE family transcriptional regulator Regulator
  MP619_RS00360 (MP619_00355) ruvB 57851..58849 (+) 999 WP_129555156.1 Holliday junction branch migration DNA helicase RuvB -
  MP619_RS00365 (MP619_00360) - 58984..59418 (+) 435 WP_129555157.1 low molecular weight protein-tyrosine-phosphatase -
  MP619_RS00370 (MP619_00365) - 59444..59845 (+) 402 WP_003049089.1 MORN repeat-containing protein -
  MP619_RS00375 (MP619_00370) - 59842..61617 (+) 1776 WP_129555158.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35627.18 Da        Isoelectric Point: 4.5345

>NTDB_id=675069 MP619_RS00355 WP_129555155.1 56705..57616(+) (comR) [Streptococcus dysgalactiae strain WJ001]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDGKLQVRESQFDEIFENYYDQLPEEEQLIIECLQATLDTLLSENINFGVELLQEYFKQTKVKLRFKQND
LILIELYLAYLDIEGMYGEYSDKVFYDSLLDNLLKQFDDFELDELFIVNKIIIDISSLSIKTNKLDNLEKTIAISQKIMA
KIQDWNRMPILKLIEWKYFLIKQKNRKQAEESYTKACLFAQITGDKYLEEQLIKEWEKDICAY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=675069 MP619_RS00355 WP_129555155.1 56705..57616(+) (comR) [Streptococcus dysgalactiae strain WJ001]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGACTAAGACTTGAGAAAGGGATTAGTCGAGAAGAATTGTGTGGAGATGA
GGCAGAGTTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATGGTAAATTACAAGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAACAATTGATTATAGAATGTTTACAGGCTACGCTAGACACTTTATTAAGTG
AAAACATCAATTTTGGTGTCGAATTATTGCAGGAATATTTTAAACAAACCAAAGTTAAGCTACGTTTTAAACAAAACGAC
TTGATACTTATTGAACTCTATCTGGCTTATCTCGATATTGAAGGGATGTATGGAGAATATTCTGATAAGGTTTTTTATGA
TTCTTTGTTAGATAACCTGTTAAAACAATTCGATGACTTTGAATTAGACGAACTGTTCATAGTTAATAAAATTATTATTG
ATATTTCTTCTTTAAGTATTAAAACTAATAAACTAGATAATCTAGAAAAGACGATTGCTATAAGTCAAAAAATCATGGCA
AAAATCCAGGATTGGAATAGAATGCCTATACTAAAGCTAATAGAATGGAAGTACTTTTTAATAAAACAAAAGAACAGAAA
ACAAGCAGAGGAATCATATACAAAGGCGTGTCTGTTTGCGCAAATAACAGGAGACAAGTATTTGGAAGAGCAATTAATCA
AAGAATGGGAGAAGGATATTTGTGCTTATTAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-296)

Helix-turn-helix (HTH_3)

(12-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

82.508

100

0.825
  comR Streptococcus pyogenes MGAS315

55

99.01

0.545
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

50.847

97.36

0.495
  comR Streptococcus mutans UA159

49.498

98.68

0.488