Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   MUG62_RS08760 Genome accession   NZ_CP094872
Coordinates   1863537..1864112 (-) Length   191 a.a.
NCBI ID   WP_001829272.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain C101     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1856034..1863031 1863537..1864112 flank 506


Gene organization within MGE regions


Location: 1856034..1864112
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUG62_RS08670 (MUG62_08670) - 1856046..1856279 (-) 234 Protein_1683 AAA family ATPase -
  MUG62_RS08675 (MUG62_08675) - 1856654..1856977 (+) 324 WP_002456098.1 hypothetical protein -
  MUG62_RS12090 - 1856960..1857094 (-) 135 WP_002439268.1 hypothetical protein -
  MUG62_RS08680 (MUG62_08680) - 1857108..1857320 (-) 213 Protein_1686 DUF771 domain-containing protein -
  MUG62_RS08685 (MUG62_08685) - 1857324..1858088 (-) 765 WP_237625885.1 phage regulatory protein/antirepressor Ant -
  MUG62_RS08690 (MUG62_08690) - 1858138..1858344 (+) 207 WP_002439266.1 hypothetical protein -
  MUG62_RS08695 (MUG62_08695) - 1858333..1858497 (-) 165 WP_002439265.1 hypothetical protein -
  MUG62_RS08700 (MUG62_08700) - 1858494..1858748 (-) 255 WP_237625886.1 helix-turn-helix transcriptional regulator -
  MUG62_RS08705 (MUG62_08705) - 1858942..1859271 (+) 330 WP_002439260.1 helix-turn-helix transcriptional regulator -
  MUG62_RS08710 (MUG62_08710) - 1859283..1859744 (+) 462 WP_002469232.1 ImmA/IrrE family metallo-endopeptidase -
  MUG62_RS08715 (MUG62_08715) - 1859760..1860278 (+) 519 WP_002439256.1 hypothetical protein -
  MUG62_RS08720 (MUG62_08720) - 1860280..1860723 (+) 444 WP_237625888.1 hypothetical protein -
  MUG62_RS08725 (MUG62_08725) - 1860796..1860990 (+) 195 WP_002439253.1 hypothetical protein -
  MUG62_RS08730 (MUG62_08730) - 1861059..1861574 (+) 516 WP_002439252.1 hypothetical protein -
  MUG62_RS08735 (MUG62_08735) - 1861576..1861911 (+) 336 WP_002439251.1 hypothetical protein -
  MUG62_RS08740 (MUG62_08740) - 1861967..1862365 (+) 399 Protein_1698 phage integrase SAM-like domain-containing protein -
  MUG62_RS08745 (MUG62_08745) - 1862471..1863031 (+) 561 WP_279594400.1 site-specific integrase -
  MUG62_RS08760 (MUG62_08760) comK/comK1 1863537..1864112 (-) 576 WP_001829272.1 competence protein ComK Regulator

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 22782.87 Da        Isoelectric Point: 9.2887

>NTDB_id=673836 MUG62_RS08760 WP_001829272.1 1863537..1864112(-) (comK/comK1) [Staphylococcus epidermidis strain C101]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN

Nucleotide


Download         Length: 576 bp        

>NTDB_id=673836 MUG62_RS08760 WP_001829272.1 1863537..1864112(-) (comK/comK1) [Staphylococcus epidermidis strain C101]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(7-158)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

76.757

96.859

0.743
  comK/comK1 Staphylococcus aureus N315

76.757

96.859

0.743