Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SITYG_RS02600 Genome accession   NZ_AP014880
Coordinates   503947..505248 (+) Length   433 a.a.
NCBI ID   WP_096362593.1    Uniprot ID   -
Organism   Streptococcus intermedius strain TYG1620     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 498947..510248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS02575 (SITYG_04890) - 499152..499754 (+) 603 WP_096362589.1 hypothetical protein -
  SITYG_RS02580 (SITYG_04900) - 499747..500733 (+) 987 WP_096362590.1 hypothetical protein -
  SITYG_RS10810 - 501163..501270 (+) 108 WP_231870254.1 hypothetical protein -
  SITYG_RS10785 - 501263..501536 (+) 274 Protein_479 type II toxin-antitoxin system RelE family toxin -
  SITYG_RS10310 (SITYG_04920) - 501659..501805 (-) 147 WP_158467585.1 hypothetical protein -
  SITYG_RS02590 (SITYG_04940) cysK 502226..503155 (-) 930 WP_096362591.1 cysteine synthase A -
  SITYG_RS02595 (SITYG_04950) - 503255..503890 (-) 636 WP_096362592.1 YigZ family protein -
  SITYG_RS02600 (SITYG_04960) comFA/cflA 503947..505248 (+) 1302 WP_096362593.1 DEAD/DEAH box helicase Machinery gene
  SITYG_RS02605 (SITYG_04970) - 505245..505910 (+) 666 WP_003078227.1 ComF family protein -
  SITYG_RS02610 (SITYG_04980) hpf 505989..506531 (+) 543 WP_003073626.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SITYG_RS02615 (SITYG_04990) rsmD 506730..507269 (+) 540 WP_048784924.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SITYG_RS02620 (SITYG_05000) coaD 507259..507756 (+) 498 WP_003078294.1 pantetheine-phosphate adenylyltransferase -
  SITYG_RS02625 (SITYG_05010) sepM 507737..508792 (+) 1056 WP_003073620.1 SepM family pheromone-processing serine protease Regulator
  SITYG_RS02630 (SITYG_05020) - 509074..509637 (+) 564 WP_096362594.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49266.07 Da        Isoelectric Point: 8.9799

>NTDB_id=67244 SITYG_RS02600 WP_096362593.1 503947..505248(+) (comFA/cflA) [Streptococcus intermedius strain TYG1620]
MIELQDCLGRIFTRSQLPLGLQQQAQTLSGMIEKKGKLWCNRCGQVVNKEKQQLPIGAYYCRSCVRLGRVRSDEKLYYFP
QAEFPKMNVLKWEGRLTDYQAKVSQGLVEAVAKQKNSLVHAVTGAGKTEMIYQVVAQVIDQGGAVCLASPRIDVCLELHR
RLQEDFSCDISLLHGESEVYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVTQSVKEQSTIIFLTATS
TDELDKKVSKGELNRLSLPRRFHGNPLIVPQKIWLENFQKYLNQKKLVPKLEQFVKKQRKTGFPLLIFASEIKRGQELAE
VLQSYFSSENVGFVASTTKNRLDIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSHSALVQIAGRVGRSMD
RPTGELLFFHDGTNFAIERAIQEIKAMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=67244 SITYG_RS02600 WP_096362593.1 503947..505248(+) (comFA/cflA) [Streptococcus intermedius strain TYG1620]
ATGATAGAATTACAAGACTGTTTAGGTCGTATCTTTACAAGAAGCCAATTACCACTAGGATTGCAGCAACAAGCTCAAAC
ATTGTCGGGAATGATAGAAAAAAAGGGGAAATTATGGTGCAATCGTTGTGGACAAGTAGTTAATAAAGAAAAACAGCAAC
TACCAATAGGTGCTTATTATTGCAGGTCATGCGTGCGATTAGGAAGGGTCAGAAGTGATGAAAAACTCTACTATTTTCCA
CAAGCAGAGTTCCCAAAAATGAATGTTTTGAAATGGGAAGGAAGGTTAACAGATTACCAAGCTAAGGTTTCTCAAGGTCT
TGTAGAGGCAGTTGCCAAACAAAAAAATAGCCTGGTTCATGCAGTCACGGGAGCTGGAAAAACAGAAATGATCTATCAGG
TGGTAGCACAAGTTATTGATCAAGGCGGGGCCGTCTGCTTGGCTAGCCCTCGAATTGATGTCTGTCTAGAACTACATCGC
AGATTGCAAGAAGATTTTAGTTGTGATATTTCACTCCTGCACGGTGAATCAGAAGTTTATTTTCGCAGTCCTCTTGTGAT
TGCCACAACGCATCAGCTTCTCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGACGAGGTGGATGCCTTTCCTTATG
TGGATAATCCGATGCTTTACCATGCCGTTACACAATCAGTAAAAGAGCAAAGTACTATAATTTTTCTAACGGCAACCTCT
ACAGATGAGCTGGATAAAAAAGTTAGCAAGGGAGAGTTGAACCGCTTAAGTCTCCCTAGACGTTTTCATGGTAACCCTTT
AATTGTTCCTCAAAAAATTTGGTTGGAAAATTTTCAAAAATACTTGAATCAAAAAAAGCTAGTTCCTAAGTTGGAACAAT
TTGTTAAAAAGCAAAGAAAAACAGGTTTTCCTCTTCTCATTTTTGCTTCTGAGATTAAAAGAGGACAAGAATTGGCAGAG
GTTCTCCAAAGTTATTTTTCCAGTGAGAACGTTGGCTTTGTAGCCTCAACGACTAAAAATCGACTTGATATTGTAGAGAA
ATTTCGACAAAAAGAAATTACAATTTTAGTAACAACGACAATTCTAGAACGTGGTGTGACTTTTCCTTGTGTAGATGTTT
TTGTGGTGGAGGCCAACCACCGTTTGTTTAGTCACAGTGCTCTGGTACAAATAGCTGGACGCGTTGGTCGCAGTATGGAT
CGTCCGACAGGTGAGCTACTCTTTTTTCATGATGGGACCAATTTTGCTATTGAACGAGCTATTCAGGAAATTAAGGCGAT
GAATCAGGAGGCTGGTTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-397)

DEAD/DEAH box helicase (DEAD)

(98-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae D39

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae R6

69.393

98.845

0.686
  comFA/cflA Streptococcus pneumoniae TIGR4

69.159

98.845

0.684
  comFA/cflA Streptococcus mitis NCTC 12261

69.014

98.383

0.679
  comFA/cflA Streptococcus mitis SK321

68.545

98.383

0.674
  comFA Lactococcus lactis subsp. cremoris KW2

54.271

91.917

0.499
  comFA Latilactobacillus sakei subsp. sakei 23K

40.465

99.307

0.402
  comFA Bacillus subtilis subsp. subtilis str. 168

38.765

93.533

0.363

Multiple sequence alignment