Detailed information NTG0671558

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA22_RS04495
• Genome accession: NZ_CP094734
• Coordinates: 995915..996958 (+)
• Length: 347 a.a.
• NCBI ID: WP_019166463.1
• Uniprot ID: A0A2A4GVQ0
• Organism: Staphylococcus delphini strain IVB6245
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 990915..1001958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA22_RS04470 (MUA22_04470)	-	991980..992705 (+)	726	WP_019166458.1	type 1 glutamine amidotransferase	-
MUA22_RS04475 (MUA22_04475)	-	992861..993859 (-)	999	WP_019166459.1	aromatic acid exporter family protein	-
MUA22_RS04480 (MUA22_04480)	map	993956..994717 (+)	762	WP_262613444.1	type I methionyl aminopeptidase	-
MUA22_RS04485 (MUA22_04485)	-	994815..995204 (+)	390	WP_262613446.1	hypothetical protein	-
MUA22_RS04490 (MUA22_04490)	liaF	995217..995918 (+)	702	WP_096557032.1	cell wall-active antibiotics response protein LiaF	-
MUA22_RS04495 (MUA22_04495)	vraS	995915..996958 (+)	1044	WP_019166463.1	sensor histidine kinase	Regulator
MUA22_RS04500 (MUA22_04500)	vraR	996948..997577 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
MUA22_RS04505 (MUA22_04505)	-	997731..998312 (-)	582	WP_019166464.1	carbonic anhydrase	-
MUA22_RS04510 (MUA22_04510)	-	998345..999691 (-)	1347	WP_262613447.1	YihY/virulence factor BrkB family protein	-
MUA22_RS04515 (MUA22_04515)	-	999907..1000194 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
MUA22_RS04520 (MUA22_04520)	-	1000202..1000660 (-)	459	WP_262613448.1	low molecular weight protein-tyrosine-phosphatase	-
MUA22_RS04525 (MUA22_04525)	-	1000794..1000997 (+)	204	WP_019166467.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39911.18 Da
• Isoelectric Point: 5.0397

>NTDB_id=671558 MUA22_RS04495 WP_019166463.1 995915..996958(+) (vraS) [Staphylococcus delphini strain IVB6245]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWVKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDDKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=671558 MUA22_RS04495 WP_019166463.1 995915..996958(+) (vraS) [Staphylococcus delphini strain IVB6245]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATCGATAA
AGTGTTTACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGGATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATCGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGGTGAAGCAA
CAAATTGTTCGTGCTTTCGAAGGCGAAACAGTGGGAATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTATCAAGCGCTTGTCCCATTGAATCAAGAACTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGGCAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAGGAAACAGATTTAGCTCCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGTGCACTGTTACTTCATTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGGATAAAATCGCTTGTGACGGATCTACAGCGCAAAGTGCCTATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTCCCTAAAGGTATTGAGGATCACCTCTTTAGGATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGAACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGATAAATTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACG
TTTCATATCGTCTCATTACCTGATGCAGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A2A4GVQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.573	100	0.836