Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   MP387_RS08965 Genome accession   NZ_CP094226
Coordinates   1844235..1845533 (-) Length   432 a.a.
NCBI ID   WP_242746562.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1839235..1850533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS08945 (MP387_08945) - 1839558..1841531 (-) 1974 WP_242746548.1 DHH family phosphoesterase -
  MP387_RS08950 (MP387_08950) - 1841688..1842866 (-) 1179 WP_242748068.1 acetyl-CoA C-acetyltransferase -
  MP387_RS08955 (MP387_08955) raiA 1842948..1843496 (-) 549 WP_000599111.1 ribosome-associated translation inhibitor RaiA -
  MP387_RS08960 (MP387_08960) comFC/cflB 1843576..1844238 (-) 663 WP_242746552.1 ComF family protein Machinery gene
  MP387_RS08965 (MP387_08965) comFA/cflA 1844235..1845533 (-) 1299 WP_242746562.1 DEAD/DEAH box helicase Machinery gene
  MP387_RS08970 (MP387_08970) - 1845590..1846225 (+) 636 WP_242746564.1 YigZ family protein -
  MP387_RS08975 (MP387_08975) - 1846241..1846684 (+) 444 WP_242746567.1 PH domain-containing protein -
  MP387_RS08980 (MP387_08980) cysK 1846781..1847707 (+) 927 WP_242746571.1 cysteine synthase A -
  MP387_RS08985 (MP387_08985) tsf 1847811..1848851 (-) 1041 WP_242746574.1 translation elongation factor Ts -
  MP387_RS08990 (MP387_08990) rpsB 1848930..1849709 (-) 780 WP_000268476.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49599.46 Da        Isoelectric Point: 7.9852

>NTDB_id=668134 MP387_RS08965 WP_242746562.1 1844235..1845533(-) (comFA/cflA) [Streptococcus oralis strain 1648]
MKVNPNYLGRLFTEKELTEEERQVAVRLPAMRKEKGKQFCQRCNSSILEEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWCGQLTPFQEKLSEGLIRAVEKKEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNTMLYYAVKNSVKEDGLRIFLTATST
DELDRKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRCLEKNQLSTKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LQVHFPDENIGFVSSITEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAINEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=668134 MP387_RS08965 WP_242746562.1 1844235..1845533(-) (comFA/cflA) [Streptococcus oralis strain 1648]
ATGAAAGTAAATCCAAATTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTGAAGAAGAACGACAGGTAGCAGTGAG
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACAGTTTTGTCAACGTTGTAATAGTTCGATTCTAGAAGAATGGTATTTGC
CTATTGGTGCCTACTATTGTAGGGAGTGTTTGCTGATGAAGCGAGTCAGGAGTGATCAAGCTTTGTACTATTTTCCGCAG
GAAGATTTTCCTAAGCAAGATGTTCTCAAATGGTGTGGTCAGTTAACCCCTTTTCAGGAAAAGTTATCAGAGGGGTTGAT
TCGAGCAGTCGAAAAGAAAGAACCGACTTTAGTTCATGCTGTGACAGGAGCTGGAAAGACAGAGATGATCTATCAAGTTG
TAGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATTGATGTGTGTTTGGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGCGATATAGCACTACTTCATGGCGAATCAGAGCCCTATTTTCGAACTCCCCTAGTAGTTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAACACTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTGAGGATATTCCTTACGGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCGCACAGGGGAATTAAAAAGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCGCTGTTTAGAGAAAAATCAATTGTCAACCAAGTTAAAGACTTATA
TTGAGAAACAGAGAAGAACAGGTTATCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAATA
CTACAGGTGCATTTCCCAGATGAGAATATCGGTTTTGTATCTTCTATCACAGAAGACCGATTAGAGCAAGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATATTGGAACGCGGAGTCACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGACTCTTTACCAAGTCTAGCTTGATTCAGATTGGTGGTCGAGTTGGACGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATGCTTCCATCAAGAAGGCAATCAATGAAATCAAGCAGATGAA
CAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

89.815

100

0.898
  comFA/cflA Streptococcus mitis SK321

89.352

100

0.894
  comFA/cflA Streptococcus pneumoniae Rx1

88.889

100

0.889
  comFA/cflA Streptococcus pneumoniae D39

88.889

100

0.889
  comFA/cflA Streptococcus pneumoniae R6

88.889

100

0.889
  comFA/cflA Streptococcus pneumoniae TIGR4

88.657

100

0.887
  comFA Lactococcus lactis subsp. cremoris KW2

52.03

91.204

0.475
  comFA Latilactobacillus sakei subsp. sakei 23K

38.952

100

0.396

Multiple sequence alignment