Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   OG293_RS15100 Genome accession   NZ_CP108867
Coordinates   3513101..3515626 (-) Length   841 a.a.
NCBI ID   WP_405999308.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00829     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3508101..3520626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG293_RS15085 (OG293_15095) - 3509572..3510132 (+) 561 WP_405999305.1 TetR/AcrR family transcriptional regulator -
  OG293_RS15090 (OG293_15100) - 3510159..3510842 (-) 684 WP_405999306.1 M23 family metallopeptidase -
  OG293_RS15095 (OG293_15105) dacB 3511382..3513010 (+) 1629 WP_405999307.1 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase -
  OG293_RS15100 (OG293_15110) clpC 3513101..3515626 (-) 2526 WP_405999308.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  OG293_RS15105 (OG293_15115) - 3516059..3516634 (+) 576 WP_405999309.1 SCO3374 family protein -
  OG293_RS15110 (OG293_15120) - 3516613..3516948 (-) 336 WP_405999310.1 Lsr2 family protein -
  OG293_RS15115 (OG293_15125) - 3517092..3517613 (-) 522 WP_405999311.1 amino-acid N-acetyltransferase -
  OG293_RS15120 (OG293_15130) - 3517624..3518019 (-) 396 WP_405999312.1 BlaI/MecI/CopY family transcriptional regulator -
  OG293_RS15125 (OG293_15135) - 3518122..3518295 (-) 174 WP_405999313.1 hypothetical protein -
  OG293_RS15130 (OG293_15140) - 3518310..3518915 (-) 606 WP_406003601.1 hypothetical protein -
  OG293_RS15135 (OG293_15145) - 3519212..3520009 (-) 798 WP_405999314.1 type III pantothenate kinase -

Sequence

Protein


Download         Length: 841 a.a.        Molecular weight: 93117.41 Da        Isoelectric Point: 5.9178

>NTDB_id=667793 OG293_RS15100 WP_405999308.1 3513101..3515626(-) (clpC) [Streptomyces sp. NBC_00829]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEAATAGGPAEGT
PSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKD
KHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLID
EAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGELI
AEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSK
TLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILED
GRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDVKSNYDRMKVKVNEELKQHFRPEFLNRVDDTVVFHQLT
EEDIIQIVDLMIAKVDERLKDRDMGLELSPTAKSLLAKKGYDPVLGARPLRRTIQREIEDILSEKILFGELRPGHIVVVD
TEGEGEEKKFTFRGEEKSALPDVPPIEQAAGGAGPNLSKDA

Nucleotide


Download         Length: 2526 bp        

>NTDB_id=667793 OG293_RS15100 WP_405999308.1 3513101..3515626(-) (clpC) [Streptomyces sp. NBC_00829]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTTATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGTCATATTCCCTTC
ACGCCCCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCTCTTCAGCTGGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTGAAGCTGGGCGCCGATCTCAACCGGG
TGCGACAGCAGGTCATCCAGCTGCTCTCCGGCTACCAGGGCAAGGAGGCCGCCACCGCAGGCGGCCCGGCCGAGGGCACG
CCCTCGACCTCGCTCGTCCTGGACCAGTTCGGCCGGAATCTCACCCAGGCCGCTCGTGAGTCCAAACTCGACCCGGTCAT
CGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTTTCCCGCCGTACGAAGAACAACCCCGTGCTCATCGGCGAGC
CCGGCGTCGGCAAGACGGCGGTCGTCGAGGGCCTTGCGCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAGGAC
AAGCACCTCTACACCCTGGACCTCGGCGCGCTGGTCGCGGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTCCTCAAGGAGATCCGCACCCGGGGCGACATCATCCTGTTCATCGACGAGCTCCACACCCTGGTGGGTGCGGGCGCCG
CCGAGGGCGCGATCGACGCCGCCAGCATCCTCAAGCCGATGCTGGCGCGGGGCGAGCTCCAGACCATCGGTGCGACCACG
CTGGACGAGTACCGCAAGCACCTGGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCCGTC
GCTGCCGCACACGATCGAGATCCTCAAGGGTCTGCGGGACCGCTACGAGGCCCACCACCGCGTCTCCATCACGGACGAGG
CGCTCGTCCAGGCCGCGACACTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGCTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCGGGCGT
CCGCCGCGACAAGGAGTCGGCCATCGACTCCCAGGACTTCGAGAAGGCGGCCTCTCTCCGCGACAAGGAGAAGCAGCTGC
TCGCCGCGAAGGCCAAGCGCGAGAAGGAATGGAAGGCCGGCGACATGGATGTCGTCGCCGAGGTCGACGGCGAGCTCATC
GCCGAAGTCCTCGCCACGGCGACCGGCATTCCCGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGTCTGCTGCGCATGGA
GGACGAGCTCCACAAGCGCGTCATCGGCCAGAAGGACGCCATCAAGGCGCTCTCGCAGGCCATTCGCCGTACGCGAGCGG
GTCTGAAGGACCCGAAGCGCCCCGGCGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTCTCCAAG
ACGCTCGCCGAATTCCTCTTCGGCGACGAGGACGCGCTGATCTCTCTCGACATGTCGGAGTTCAGCGAGAAGCACACGGT
TTCCCGCCTCTTCGGTTCCCCGCCCGGATACGTGGGTTACGAAGAGGGCGGCCAGCTCACCGAGAAGGTGCGCCGGAAGC
CGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCCGATATCTTCAATTCCCTTCTGCAGATCCTGGAGGAC
GGTCGCCTGACCGACTCCCAGGGCCGCGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGGACCCG
GGACATCTCGAAGGGCTTCAACCTGGGCTTCGCGGCTCAGGGCGACGTCAAGTCGAACTACGACCGGATGAAGGTCAAGG
TCAACGAGGAGCTGAAGCAGCACTTCCGGCCCGAGTTCCTGAACCGTGTCGACGACACGGTCGTCTTCCACCAGCTGACC
GAGGAAGACATCATCCAGATCGTCGACCTCATGATCGCCAAGGTGGACGAGCGTCTGAAGGACCGCGACATGGGTCTGGA
GCTCAGCCCCACGGCCAAGTCGCTGCTCGCCAAGAAGGGCTACGACCCGGTTCTGGGCGCCAGGCCGCTGCGCCGGACGA
TCCAGCGCGAGATCGAGGACATCCTGTCGGAGAAGATCCTCTTCGGCGAGCTGCGCCCCGGTCACATCGTGGTCGTGGAC
ACCGAGGGCGAGGGTGAGGAGAAGAAGTTCACCTTCCGCGGCGAGGAGAAGTCCGCGCTGCCGGACGTCCCGCCGATCGA
GCAGGCCGCCGGCGGAGCCGGGCCGAACCTGTCCAAGGACGCGTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(541-712)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(93-142)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(16-68)

ATPase family associated with various cellular activities (AAA) (AAA)

(209-329)

AAA lid domain (AAA_lid_9)

(349-449)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(719-799)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

61.347

95.363

0.585
  clpC Streptococcus mutans UA159

44.578

98.692

0.44
  clpC Streptococcus thermophilus LMD-9

43.452

99.881

0.434
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

44.198

96.314

0.426
  clpC Streptococcus pneumoniae Rx1

44.334

95.482

0.423
  clpC Streptococcus pneumoniae D39

44.334

95.482

0.423
  clpC Streptococcus pneumoniae TIGR4

44.361

94.887

0.421
  clpE Streptococcus mutans UA159

53.674

74.435

0.4
  clpC Streptococcus thermophilus LMG 18311

49.477

79.548

0.394
  clpE Streptococcus pneumoniae TIGR4

52.488

74.078

0.389
  clpE Streptococcus pneumoniae D39

52.327

74.078

0.388
  clpE Streptococcus pneumoniae R6

52.327

74.078

0.388
  clpE Streptococcus pneumoniae Rx1

52.327

74.078

0.388
  clpC Lactococcus lactis subsp. cremoris KW2

52.419

73.722

0.386

Multiple sequence alignment