Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   SCSC_RS09370 Genome accession   NZ_AP014647
Coordinates   1897110..1898435 (-) Length   441 a.a.
NCBI ID   WP_280523174.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. constellatus strain CCUG 24889     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1892110..1903435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCSC_RS09350 (SCSC_1927) - 1893462..1896041 (+) 2580 WP_006270322.1 YfhO family protein -
  SCSC_RS09365 (SCSC_1930) comE 1896361..1897110 (-) 750 WP_003071650.1 competence system response regulator transcription factor ComE Regulator
  SCSC_RS09370 (SCSC_1931) comD/comD2 1897110..1898435 (-) 1326 WP_280523174.1 GHKL domain-containing protein Regulator
  SCSC_RS09375 (SCSC_1932) - 1898452..1898598 (-) 147 WP_006270349.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SCSC_RS09385 (SCSC_1934) rlmH 1898881..1899360 (-) 480 WP_006270335.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SCSC_RS09390 (SCSC_1935) htrA 1899565..1900755 (+) 1191 WP_006270334.1 trypsin-like peptidase domain-containing protein Regulator
  SCSC_RS09395 (SCSC_1936) spo0J 1900810..1901577 (+) 768 WP_003071657.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51968.85 Da        Isoelectric Point: 9.0710

>NTDB_id=66599 SCSC_RS09370 WP_280523174.1 1897110..1898435(-) (comD/comD2) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MVKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKV
KKHSSLFLALFLSLAVSGSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKVDFKDKIVQ
LNFYLLFIHFLLNVSHWLSNMKSLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVSLY
NEIRGFRHDYGGMLASFQSAIHTGNIREVERIYQEVLVNANLQLRSDKYTYFDLNNIGDSALRSVMIQTLFKARDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRQLDLEMIYQTDFSTKGE
GRGLGLSNIKEIINNYEGIILDTNIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=66599 SCSC_RS09370 WP_280523174.1 1897110..1898435(-) (comD/comD2) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATAGTGAAAATAGAATTTATACATTGGATTATATTCTCAATTATAGAAGCTGTTTCTGTTGTATATTGTTATAAGAAGAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAA
TACATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTT
AAAAAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTTATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTT
TCATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGTTGATTTCAAAGATAAGATTGTACAG
TTAAATTTTTATCTATTATTCATTCATTTTTTATTAAATGTATCGCATTGGCTTAGCAATATGAAAAGTTTAAATAGTTT
TTCTAGTATGATTGCGACGATTTGCTTTTTGATGTTTATGTCAATTTTATTCTACTTACAATCTATTCGTGAAAAATATG
AAAAAGAGGAGCAAATTAAACAAAAAGAACGAGAACAGCTACAACTACAAAAGTATACAGATGAAATTGTGAGTCTTTAC
AATGAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTCCAATCTGCCATTCATACAGGTAATATAAG
AGAAGTAGAACGAATTTATCAAGAAGTACTAGTAAATGCTAATTTACAACTTCGTTCAGATAAATATACTTATTTTGATT
TAAATAACATTGGGGATTCAGCGCTTAGAAGCGTTATGATACAAACCTTGTTTAAGGCACGTGATTATAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTCAAGCCTTTACCGATTAAATTATTAGATCTAGTTAGAATGACAAGTGTTCTTTTAAA
TAATGCCATAGAAGGAGCAGCAGAAAGTTATCAAAAAACAATGAATGTTTCTTTGGTAGATTTGGATACAGAAACTATCT
TAGTCATTCAAAATTCACGTAAAAAAAGACAACTAGACTTAGAAATGATTTATCAAACCGATTTTTCAACAAAGGGCGAG
GGACGAGGTTTAGGTTTAAGCAATATCAAAGAAATTATTAATAACTATGAAGGAATTATTCTTGATACAAACATTGAGGA
TGAATATTTTACACAAGTAATGAGAGTAAGGAAAGAAGGTCTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

53.846

100

0.54
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.11

99.32

0.537
  comD Streptococcus mitis SK321

47.704

88.889

0.424
  comD/comD2 Streptococcus pneumoniae TIGR4

48.67

85.261

0.415
  comD Streptococcus mitis NCTC 12261

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae Rx1

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae D39

48.138

85.261

0.41
  comD/comD1 Streptococcus pneumoniae R6

48.138

85.261

0.41

Multiple sequence alignment