Detailed information NTG0663193

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MNY35_RS14050
• Genome accession: NZ_CP093298
• Coordinates: 2926741..2927904 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus amyloliquefaciens strain MN-13
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2921741..2932904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MNY35_RS14030 (MNY35_14020)	-	2922157..2923353 (+)	1197	WP_015418338.1	glycosyltransferase	-
MNY35_RS14035 (MNY35_14025)	-	2923486..2924562 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
MNY35_RS14040 (MNY35_14030)	-	2924652..2925866 (-)	1215	WP_033575220.1	LCP family protein	-
MNY35_RS14045 (MNY35_14035)	-	2925871..2926518 (-)	648	WP_003151384.1	YigZ family protein	-
MNY35_RS14050 (MNY35_14040)	degS	2926741..2927904 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
MNY35_RS14055 (MNY35_14045)	degU	2927981..2928670 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MNY35_RS14060 (MNY35_14050)	-	2928768..2929616 (+)	849	WP_015418336.1	DegV family protein	-
MNY35_RS14065 (MNY35_14055)	comFA	2929724..2931109 (+)	1386	WP_033575221.1	DEAD/DEAH box helicase	Machinery gene
MNY35_RS14070 (MNY35_14060)	-	2931167..2931451 (+)	285	WP_003151389.1	competence protein ComFB	-
MNY35_RS14075 (MNY35_14065)	comFC	2931457..2932146 (+)	690	WP_197093073.1	phosphoribosyltransferase family protein	Machinery gene
MNY35_RS14080 (MNY35_14070)	-	2932220..2932639 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=663193 MNY35_RS14050 WP_007407484.1 2926741..2927904(+) (degS) [Bacillus amyloliquefaciens strain MN-13]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=663193 MNY35_RS14050 WP_007407484.1 2926741..2927904(+) (degS) [Bacillus amyloliquefaciens strain MN-13]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951