Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ML603_RS01850 Genome accession   NZ_CP092887
Coordinates   348514..349200 (+) Length   228 a.a.
NCBI ID   WP_003049736.1    Uniprot ID   A0A9X5LVW0
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 343514..354200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS01825 (ML603_01825) ktrB 343623..344999 (-) 1377 WP_012766594.1 potassium uptake transporter channel subunit KtrB -
  ML603_RS01830 (ML603_01830) rsmG 345083..345796 (-) 714 WP_241067402.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ML603_RS01835 (ML603_01835) - 345949..346506 (+) 558 WP_143927203.1 LemA family protein -
  ML603_RS01840 (ML603_01840) htpX 346551..347444 (+) 894 WP_241067404.1 zinc metalloprotease HtpX -
  ML603_RS01845 (ML603_01845) - 347710..348243 (+) 534 WP_138126948.1 YceD family protein -
  ML603_RS01850 (ML603_01850) covR 348514..349200 (+) 687 WP_003049736.1 two-component system response regulator CovR Regulator
  ML603_RS01855 (ML603_01855) - 349206..350705 (+) 1500 WP_241067406.1 HAMP domain-containing histidine kinase -
  ML603_RS01860 (ML603_01860) nrdR 350911..351405 (+) 495 WP_003049740.1 transcriptional regulator NrdR -
  ML603_RS01865 (ML603_01865) - 351389..352567 (+) 1179 WP_241067407.1 DnaD domain protein -
  ML603_RS01870 (ML603_01870) dnaI 352568..353470 (+) 903 WP_003058998.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26567.56 Da        Isoelectric Point: 4.6541

>NTDB_id=660916 ML603_RS01850 WP_003049736.1 348514..349200(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKTPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLSILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=660916 ML603_RS01850 WP_003049736.1 348514..349200(+) (covR) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAACCTTGCACGGTTCGTTTCACTCGAATTGCAACATGAAGGTTA
CGAAGTAACTGTTGAAGTAAATGGTCGCGAAGGTTTGGAAACTGCCTTAGAAAAGGATTTTGACTTGATCCTCCTTGACC
TAATGCTTCCTGAAATGGATGGTTTTGAAGTGACTCGTCGCTTACAAACTGAAAAAACAACTTACATCATGATGATGACT
GCGCGTGATTCGATTATGGATGTGGTTGCGGGATTAGACCGTGGAGCGGATGATTACATTGTGAAGCCATTTGCTATTGA
AGAGTTATTGGCTCGTATCCGTGCCATTTTCCGTCGCCAAGATATCGAATCTGAGAAGAAAACCCCTAGTCAAGGGATTT
ACCGTGATTTGGTCTTGAACCCACAAAACCGTTCAGTTAACAGAGGAGATGATGAAATCTCTTTGACGAAACGTGAATAT
GATTTGCTTAGCATTTTGATGACCAATATGAATCGTGTCATGACACGTGAAGAGTTATTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAATGTAGTGGATGTTTATATTCGTTACCTTCGCGGCAAAATCGATATTCCAGGTAAGGAGTCTT
ATATCCAAACCGTTCGCGGTATGGGCTATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.401

99.561

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425