Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OG194_RS20115 Genome accession   NZ_CP108427
Coordinates   4544848..4545906 (+) Length   352 a.a.
NCBI ID   WP_327407138.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_01288     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4539848..4550906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG194_RS20100 (OG194_20075) - 4540529..4541395 (+) 867 WP_327402208.1 hypothetical protein -
  OG194_RS20105 (OG194_20080) - 4541406..4543103 (-) 1698 WP_327402209.1 hypothetical protein -
  OG194_RS20110 (OG194_20085) radA/sms 4543302..4544711 (+) 1410 WP_327402210.1 DNA repair protein RadA Machinery gene
  OG194_RS20115 (OG194_20090) disA 4544848..4545906 (+) 1059 WP_327407138.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OG194_RS20120 (OG194_20095) - 4545926..4546753 (-) 828 WP_327402211.1 hypothetical protein -
  OG194_RS20125 (OG194_20100) - 4546959..4547903 (+) 945 WP_327402212.1 A/G-specific adenine glycosylase -
  OG194_RS20130 (OG194_20105) - 4548245..4548784 (+) 540 WP_019064956.1 SigE family RNA polymerase sigma factor -
  OG194_RS20135 (OG194_20110) - 4548781..4549461 (+) 681 WP_327407139.1 hypothetical protein -
  OG194_RS20140 (OG194_20115) cseB 4549626..4550333 (+) 708 WP_327402213.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38066.67 Da        Isoelectric Point: 4.9024

>NTDB_id=660410 OG194_RS20115 WP_327407138.1 4544848..4545906(+) (disA) [Streptomyces sp. NBC_01288]
MRASLSAAAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFILDVEFTATRLRELCKLDGGIVVSSDLSKILRAG
VQLVPDPNIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSTVVQRLEMVRLIATEIAEYVVELGTDGRLLSLQLEELIAGVEPERELVVRDYVPEPTAKRS
RTVNEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=660410 OG194_RS20115 WP_327407138.1 4544848..4545906(+) (disA) [Streptomyces sp. NBC_01288]
ATGCGCGCCTCACTGAGCGCCGCGGCCCCTGGCACGGCCCTGCGCGACGGCCTGGAGAGAATCCTCCGCGGCAACACGGG
CGGCCTCATCGTGCTCGGTTCCGACAAGACCGTAGAAGCGATGTGCACAGGCGGTTTCATCCTGGACGTGGAGTTCACGG
CCACGCGCCTACGAGAACTCTGCAAGCTGGACGGCGGCATCGTCGTCTCCTCGGACCTCTCCAAGATCCTTCGAGCGGGC
GTCCAGCTGGTCCCCGACCCCAACATCCCCACCGAGGAGACGGGCACCCGTCACCGCACGGCGGACCGAGTGAGCAAACA
GGTCTCCTTCCCGGTGGTCTCCGTCTCCCAGTCCATGCGCCTGATCGCCCTCTACGTGGACGGCCAACGCCGCGTACTGG
AGGACTCGGCGGCGATCCTGTCCCGCGCCAACCAAGCCCTCGCCACCCTGGAGCGCTACAAACTCCGCCTGGACGAGGTG
GCGGGAACGCTGTCGGCCCTGGAGATCGAGGACCTGGTGACGGTCCGAGACGTGTCAACCGTGGTCCAACGCCTGGAAAT
GGTCCGCCTGATCGCGACCGAGATCGCCGAATACGTCGTGGAGCTCGGCACGGACGGCCGCCTGCTCTCCCTCCAGCTGG
AGGAGTTGATCGCGGGCGTGGAACCGGAACGCGAACTGGTCGTACGCGACTACGTCCCCGAGCCCACGGCCAAACGCTCC
CGCACGGTGAACGAAGCCCTGGCCGAACTGGACGCCCTCTCTCACGCGGAGCTCCTCGAACTCCCCACCGTGGCCCGCGC
GTTGGGCTACACCGGCTCCCCCGAGGCCCTCGACTCGGCGGTGTCCCCCCGAGGCTTCCGCCTCCTGGCCAAGGTCCCGC
GCCTCCCCGGCGCGATCATCGACCGCCTGGTGGAGCACTTCGGAGGCCTTCAGAAACTCCTGGCGGCAAGCGTCGACGAC
CTCCAGACAGTGGACGGCGTAGGCGAGGCAAGGGCCCGCAGCGTCCGAGAGGGCCTCTCCCGCCTGGCGGAATCGTCAAT
CCTGGAACGCTACGTATAA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)

Helix-hairpin-helix motif (HHH_2)

(302-337)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.376

98.295

0.446