Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SMUNUM_RS09000 Genome accession   NZ_AP014571
Coordinates   1820877..1821569 (-) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1815877..1826569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS08975 (SMNUM_1704) - 1815936..1816562 (-) 627 WP_002265453.1 hypothetical protein -
  SMUNUM_RS08980 (SMNUM_1705) der 1816637..1817947 (-) 1311 WP_002297146.1 ribosome biogenesis GTPase Der -
  SMUNUM_RS08985 (SMNUM_1706) dnaI 1817960..1818859 (-) 900 WP_002267936.1 primosomal protein DnaI -
  SMUNUM_RS08990 (SMNUM_1707) - 1818860..1820029 (-) 1170 WP_002262119.1 DnaD domain protein -
  SMUNUM_RS08995 (SMNUM_1708) nrdR 1820016..1820507 (-) 492 WP_002262120.1 transcriptional regulator NrdR -
  SMUNUM_RS09000 (SMNUM_1709) covR 1820877..1821569 (-) 693 WP_002262121.1 response regulator GcrR Regulator
  SMUNUM_RS09005 (SMNUM_1710) - 1821925..1822461 (-) 537 WP_002262122.1 YceD family protein -
  SMUNUM_RS09010 (SMNUM_1711) - 1822454..1823029 (-) 576 WP_002265122.1 TetR/AcrR family transcriptional regulator -
  SMUNUM_RS09015 (SMNUM_1712) - 1823137..1823844 (+) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  SMUNUM_RS09020 (SMNUM_1713) - 1823846..1826458 (+) 2613 WP_286216619.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=66001 SMUNUM_RS09000 WP_002262121.1 1820877..1821569(-) (covR) [Streptococcus mutans LP13]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=66001 SMUNUM_RS09000 WP_002262121.1 1820877..1821569(-) (covR) [Streptococcus mutans LP13]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGATACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTTATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAGACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment