Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MKI65_RS10250 Genome accession   NZ_CP092565
Coordinates   2062892..2063608 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain MRSA-WC061     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2057892..2068608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKI65_RS10220 (MKI65_002027) - 2058109..2058735 (+) 627 WP_000522381.1 nitroreductase family protein -
  MKI65_RS10225 (MKI65_002028) - 2059096..2059881 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  MKI65_RS14220 (MKI65_002029) - 2060481..2060615 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  MKI65_RS10235 (MKI65_002030) - 2060851..2061414 (+) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  MKI65_RS10240 (MKI65_002031) - 2061417..2061560 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  MKI65_RS10245 (MKI65_002032) - 2061590..2062873 (+) 1284 WP_000447888.1 sensor histidine kinase -
  MKI65_RS10250 (MKI65_002033) agrA 2062892..2063608 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  MKI65_RS10255 (MKI65_002034) - 2063680..2063789 (+) 110 Protein_1986 hypothetical protein -
  MKI65_RS10260 (MKI65_002035) - 2063977..2064936 (-) 960 WP_001253312.1 carbohydrate kinase -
  MKI65_RS10265 (MKI65_002036) - 2064933..2066417 (-) 1485 WP_000141432.1 glycoside hydrolase family 32 protein -
  MKI65_RS10270 (MKI65_002037) - 2066566..2067516 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=658964 MKI65_RS10250 WP_000688492.1 2062892..2063608(+) (agrA) [Staphylococcus aureus strain MRSA-WC061]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=658964 MKI65_RS10250 WP_000688492.1 2062892..2063608(+) (agrA) [Staphylococcus aureus strain MRSA-WC061]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1