Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MKI66_RS05985 Genome accession   NZ_CP092547
Coordinates   1225959..1226762 (+) Length   267 a.a.
NCBI ID   WP_001835067.1    Uniprot ID   -
Organism   Staphylococcus aureus strain VMRSA-WC083     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1220959..1231762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKI66_RS05965 (MKI66_001173) sucC 1221004..1222170 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  MKI66_RS05970 (MKI66_001174) sucD 1222192..1223100 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  MKI66_RS05975 (MKI66_001175) - 1223327..1224445 (+) 1119 WP_001041666.1 LysM peptidoglycan-binding domain-containing protein -
  MKI66_RS05980 (MKI66_001176) fmhC 1224473..1225717 (+) 1245 WP_000672869.1 FemA/FemB family glycyltransferase FmhC -
  MKI66_RS05985 (MKI66_001177) dprA 1225959..1226762 (+) 804 WP_001835067.1 DNA-processing protein DprA Machinery gene
  MKI66_RS05990 (MKI66_001178) topA 1226936..1229011 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  MKI66_RS05995 (MKI66_001179) trmFO 1229167..1230474 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30652.45 Da        Isoelectric Point: 9.1348

>NTDB_id=658593 MKI66_RS05985 WP_001835067.1 1225959..1226762(+) (dprA) [Staphylococcus aureus strain VMRSA-WC083]
MAYPNVIKEEGRKKDSYLCEWVNREENVLLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFY
KGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPK
STLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPM
TKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 804 bp        

>NTDB_id=658593 MKI66_RS05985 WP_001835067.1 1225959..1226762(+) (dprA) [Staphylococcus aureus strain VMRSA-WC083]
ATGGCATATCCTAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAA
TGTTCTTTTATTACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAG
TAAGTTACATTACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTAT
AAAGGGAACATCAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACA
GTCTTTAGAATTTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAA
TGGCACATCAAATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAA
AGTACATTAGCATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAA
ATATAGATTTCCTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTG
GCAGTCACATCACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATG
ACAAAAGGTAATTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATAT
TTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(49-256)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

100

100

1
  dprA Staphylococcus aureus MW2

99.625

100

0.996
  dprA Streptococcus mutans UA159

38.258

98.876

0.378
  dprA Legionella pneumophila strain ERS1305867

42.06

87.266

0.367