Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT59_RS36220 Genome accession   NZ_CP108094
Coordinates   8154220..8154861 (+) Length   213 a.a.
NCBI ID   WP_266466379.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00243     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8149220..8159861
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT59_RS36200 (OHT59_36215) - 8150063..8150815 (-) 753 WP_326724037.1 transglycosylase SLT domain-containing protein -
  OHT59_RS36205 (OHT59_36220) - 8151115..8152200 (-) 1086 WP_326724038.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHT59_RS36210 (OHT59_36225) - 8152197..8152892 (-) 696 WP_326724039.1 SDR family oxidoreductase -
  OHT59_RS36215 (OHT59_36230) - 8153082..8154227 (+) 1146 WP_326724040.1 GAF domain-containing sensor histidine kinase -
  OHT59_RS36220 (OHT59_36235) vraR 8154220..8154861 (+) 642 WP_266466379.1 response regulator transcription factor Regulator
  OHT59_RS36225 (OHT59_36240) chpE 8155006..8155254 (+) 249 WP_266466382.1 chaplin ChpE -
  OHT59_RS36230 (OHT59_36245) - 8155483..8155722 (+) 240 WP_266466385.1 chaplin -
  OHT59_RS36235 (OHT59_36250) - 8155919..8156707 (-) 789 WP_326724041.1 hypothetical protein -
  OHT59_RS36240 (OHT59_36255) - 8156829..8157620 (+) 792 WP_266466391.1 ABC transporter ATP-binding protein -
  OHT59_RS36245 (OHT59_36260) - 8157714..8158148 (+) 435 WP_326724042.1 NfeD family protein -
  OHT59_RS36250 (OHT59_36265) - 8158279..8159214 (+) 936 WP_326724043.1 SPFH domain-containing protein -
  OHT59_RS36255 (OHT59_36270) - 8159284..8159790 (-) 507 WP_266466397.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22953.33 Da        Isoelectric Point: 5.6857

>NTDB_id=653473 OHT59_RS36220 WP_266466379.1 8154220..8154861(+) (vraR) [Streptomyces sp. NBC_00243]
MADAIKVLLVDDHQVVRRGLRTFLEIQDDIEVVGEASDGAEGVARAEELKPDVVLMDVRMPGMDGIDALRKLRELTNPAR
VLIVTSFTEKRTVVPALRAGAAGYVYKDVDPEALAGAIRSVHAGHILLQPEVAGVLLSQEEVNSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=653473 OHT59_RS36220 WP_266466379.1 8154220..8154861(+) (vraR) [Streptomyces sp. NBC_00243]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAAGTGGTCCGCCGGGGCCTGCGCACCTTCCTCGAGATACA
GGACGACATCGAAGTCGTGGGAGAGGCGTCCGACGGCGCCGAAGGAGTCGCCCGCGCCGAGGAGTTGAAGCCCGACGTCG
TCCTCATGGACGTCAGGATGCCGGGCATGGACGGCATCGACGCGCTGCGCAAGCTCCGCGAACTCACCAACCCCGCACGG
GTGTTGATCGTCACCAGCTTCACCGAGAAGCGCACGGTCGTCCCGGCCCTGCGCGCGGGCGCCGCCGGGTACGTGTACAA
GGACGTGGACCCCGAAGCGCTCGCCGGCGCCATCCGTTCCGTGCACGCCGGGCACATCCTGCTCCAGCCCGAGGTGGCGG
GCGTCCTGCTGTCCCAGGAGGAGGTCAACTCGGGTCAGGGGAGAGGAGGTTCACTCACCGAGCGGGAGCGCGAGGTGCTC
GGCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCGCGCGCTCGTCCTCTCCGAAAAGACCGTCAAGACGCATGT
CTCGAACATCCTGATGAAGCTCGACCTCGCCGACCGTACGCAGGCCGCGCTGTGGGCCGTACGGCACGGTGCGGCCGGGT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.411

97.183

0.441
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

100

0.404
  letA Legionella pneumophila str. Paris

36.667

98.592

0.362
  letA Legionella pneumophila strain ERS1305867

36.667

98.592

0.362