Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG386_RS32430 Genome accession   NZ_CP108067
Coordinates   7264675..7265337 (+) Length   220 a.a.
NCBI ID   WP_328791038.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00273     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7259675..7270337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG386_RS32410 (OG386_32420) - 7260501..7261181 (-) 681 WP_328791034.1 transglycosylase SLT domain-containing protein -
  OG386_RS32415 (OG386_32425) - 7261464..7262615 (-) 1152 WP_328791035.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG386_RS32420 (OG386_32430) - 7262612..7263376 (-) 765 WP_328791036.1 SDR family NAD(P)-dependent oxidoreductase -
  OG386_RS32425 (OG386_32435) - 7263534..7264682 (+) 1149 WP_328791037.1 GAF domain-containing sensor histidine kinase -
  OG386_RS32430 (OG386_32440) vraR 7264675..7265337 (+) 663 WP_328791038.1 response regulator transcription factor Regulator
  OG386_RS32435 (OG386_32445) - 7265487..7265732 (+) 246 WP_323185303.1 chaplin -
  OG386_RS32440 (OG386_32450) - 7265909..7266691 (-) 783 WP_328791039.1 hypothetical protein -
  OG386_RS32445 (OG386_32455) - 7266825..7267619 (+) 795 WP_030010491.1 ABC transporter ATP-binding protein -
  OG386_RS32450 (OG386_32460) - 7267704..7268132 (+) 429 WP_301372001.1 NfeD family protein -
  OG386_RS32455 (OG386_32465) - 7268217..7269203 (+) 987 WP_327386172.1 SPFH domain-containing protein -
  OG386_RS32460 (OG386_32470) - 7269295..7270065 (+) 771 WP_327386173.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23722.00 Da        Isoelectric Point: 5.0209

>NTDB_id=652508 OG386_RS32430 WP_328791038.1 7264675..7265337(+) (vraR) [Streptomyces sp. NBC_00273]
MADSTGRSGSGIRVLLVDDHQVVRRGLRTFLEVQEDIEVVGEASDGEEGIARAEELGPDVILMDIKMPGTDGIEALRRLR
ELANPARVLIVTSFTEQRTVVPALRAGAAGYVYKDIDPEALAGAIRSVHAGHVLLQPEVALALLSQEEQGSPAGRPGSLT
DREREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGIAE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=652508 OG386_RS32430 WP_328791038.1 7264675..7265337(+) (vraR) [Streptomyces sp. NBC_00273]
GTGGCTGACAGCACCGGCCGGAGCGGCAGCGGCATTCGAGTACTGCTGGTCGACGACCACCAGGTGGTCCGGCGGGGCCT
GCGGACCTTCCTGGAGGTCCAGGAGGACATCGAGGTGGTCGGCGAGGCCTCCGACGGCGAAGAGGGCATCGCCCGCGCCG
AGGAGCTGGGGCCCGACGTGATCCTGATGGACATCAAGATGCCGGGCACCGACGGCATCGAGGCGCTGCGCAGGTTGCGC
GAGCTGGCGAACCCGGCCCGCGTGCTGATCGTCACCAGCTTCACCGAGCAGCGGACCGTGGTCCCCGCCCTGCGGGCCGG
CGCGGCCGGATACGTCTACAAGGACATCGACCCGGAGGCGCTGGCCGGAGCCATCCGCTCCGTCCACGCTGGCCACGTGC
TCCTCCAGCCCGAGGTGGCCCTCGCCCTGCTCTCCCAGGAGGAGCAGGGTTCCCCGGCGGGCCGGCCCGGCTCGCTGACC
GACCGCGAACGCGAGGTCCTGGGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATCGCCCGGGCCCTGGTCCTCTCCGA
GAAGACGGTCAAGACCCACGTCTCGAACATCCTGATGAAGTTGGACCTTTCCGATCGGACCCAGGCCGCATTGTGGGCGG
TCAGACACGGGATCGCCGAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-213)

Response regulator receiver domain (Response_reg)

(14-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

95

0.427
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.395
  letA Legionella pneumophila str. Paris

37.736

96.364

0.364
  letA Legionella pneumophila strain ERS1305867

37.736

96.364

0.364