Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SPYJRS4_RS00330 Genome accession   NZ_AP012335
Coordinates   54234..55145 (+) Length   303 a.a.
NCBI ID   WP_002986681.1    Uniprot ID   -
Organism   Streptococcus pyogenes JRS4     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 49234..60145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYJRS4_RS00310 (SPYJRS4_0033) purE 49683..50174 (+) 492 WP_021340277.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  SPYJRS4_RS00315 (SPYJRS4_0034) purK 50161..51234 (+) 1074 WP_011888523.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SPYJRS4_RS00320 (SPYJRS4_0035) - 51255..52595 (+) 1341 WP_011184068.1 hypothetical protein -
  SPYJRS4_RS00325 (SPYJRS4_0038) purB 52811..54103 (+) 1293 WP_011184069.1 adenylosuccinate lyase -
  SPYJRS4_RS00330 (SPYJRS4_0039) comR 54234..55145 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  SPYJRS4_RS00335 (SPYJRS4_0040) ruvB 55371..56369 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  SPYJRS4_RS00340 (SPYJRS4_0041) - 56507..56944 (+) 438 WP_002994668.1 low molecular weight phosphotyrosine protein phosphatase -
  SPYJRS4_RS00345 (SPYJRS4_0042) - 56967..57368 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  SPYJRS4_RS00350 (SPYJRS4_0043) - 57365..59140 (+) 1776 WP_011184071.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35757.27 Da        Isoelectric Point: 4.4858

>NTDB_id=65153 SPYJRS4_RS00330 WP_002986681.1 54234..55145(+) (comR) [Streptococcus pyogenes JRS4]
MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSIPSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELK
YLILRTPTYMDDGKLQVREEQFDEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSLSLKNNRLDNLEKAIEMSQKIMA
KIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKACLFAQMTADQYLENKLIQEWEKDVKSY

Nucleotide


Download         Length: 912 bp        

>NTDB_id=65153 SPYJRS4_RS00330 WP_002986681.1 54234..55145(+) (comR) [Streptococcus pyogenes JRS4]
ATGTTAGAACATTTTGGTGGAAAAGTAAAAGTGTTAAGACTTGAAAAGAGGATTAGTCGCGAGGACTTGTGTGGGGATGA
GTCTGAACTTTCTGTTCGTCAATTAGCACGGATAGAACTAGGTCAATCCATACCAAGTTTAAGTAAGGTTATTTTTATTG
CAAAAGCCTTAAACGTTAGTGTCGGTTACTTAACTGATGGTGCTGATTTAGAACTACCTAAGCGTTACAAAGAATTAAAA
TACCTTATCTTAAGGACACCAACTTACATGGATGATGGAAAATTACAAGTACGAGAAGAGCAGTTTGATGAAATTTTTGA
GGATTATTATGATAAATTACCAGAGGAAGAGAAAATAATCATTGATTGTTTACAGGCAACTTTAGATACTTTATTGAGTG
AGAATACTAACTTTGGCATTGACTTACTTCAAGAATATTTTAATCAAATAAAGACTAAGGTACGCTTTAGGCAAAATGAT
TTAATACTTCTAGAATTATATTTAGCTTATCTTGATATTGAGGGAATGGATGGACAATATTCAGATAAGATTTTTTATGA
TTCTTTATTAGATAATCTATCAGAACAATTTGAACAATTTGAATTAGATGAATTATTTATAGTTAATAAGATTATCATTG
ATATTTCATCACTAAGCTTAAAAAATAACCGACTTGATAATTTAGAAAAAGCGATTGAAATGAGTCAAAAAATTATGGCG
AAAATTCAAGATTGGAATAGAATGCCTATTTTAAAACTAATAGAATGGAAATATTTTTTAATCAAACAAAAAGATATAAT
AAAAGCAGAACAATCATTTATGAAGGCATGTTTGTTCGCCCAAATGACAGCTGATCAGTATTTGGAAAACAAGTTAATTC
AAGAGTGGGAAAAAGATGTTAAAAGTTATTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(12-64)

ComR tetratricopeptide (ComR_TPR)

(73-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

100

100

1
  comR Streptococcus pyogenes MGAS315

58.472

99.34

0.581
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

51.37

96.37

0.495
  comR Streptococcus mutans UA159

46.358

99.67

0.462

Multiple sequence alignment