Detailed information NTG0651264

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: L3474_RS08390
• Genome accession: NZ_CP091450
• Coordinates: 1671580..1672647 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain 3641/15
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1666580..1677647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3474_RS08365 (L3474_08310)	treR	1666667..1667377 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
L3474_RS08370 (L3474_08315)	-	1667534..1668677 (+)	1144	Protein_1661	transposase	-
L3474_RS08375 (L3474_08320)	-	1668844..1670190 (+)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
L3474_RS08380 (L3474_08325)	-	1670383..1670568 (+)	186	Protein_1663	transposase	-
L3474_RS08385 (L3474_08330)	amiF	1670643..1671569 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
L3474_RS08390 (L3474_08335)	amiE	1671580..1672647 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
L3474_RS08395 (L3474_08340)	amiD	1672656..1673582 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
L3474_RS08400 (L3474_08345)	amiC	1673582..1675078 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
L3474_RS08405 (L3474_08350)	amiA3	1675145..1677124 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=651264 L3474_RS08390 WP_000159553.1 1671580..1672647(-) (amiE) [Streptococcus pneumoniae strain 3641/15]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=651264 L3474_RS08390 WP_000159553.1 1671580..1672647(-) (amiE) [Streptococcus pneumoniae strain 3641/15]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541