Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   L3474_RS08365 Genome accession   NZ_CP091450
Coordinates   1666667..1667377 (+) Length   236 a.a.
NCBI ID   WP_000760673.1    Uniprot ID   A0A062WVH4
Organism   Streptococcus pneumoniae strain 3641/15     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1667534..1670568 1666667..1667377 flank 157


Gene organization within MGE regions


Location: 1666667..1670568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3474_RS08365 (L3474_08310) treR 1666667..1667377 (+) 711 WP_000760673.1 trehalose operon repressor Regulator
  L3474_RS08370 (L3474_08315) - 1667534..1668677 (+) 1144 Protein_1661 transposase -
  L3474_RS08375 (L3474_08320) - 1668844..1670190 (+) 1347 WP_001814919.1 IS1380-like element ISSpn5 family transposase -
  L3474_RS08380 (L3474_08325) - 1670383..1670568 (+) 186 Protein_1663 transposase -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27607.78 Da        Isoelectric Point: 8.9698

>NTDB_id=651262 L3474_RS08365 WP_000760673.1 1666667..1667377(+) (treR) [Streptococcus pneumoniae strain 3641/15]
MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVRKALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLT
SYQELVKELGLRSKTNVVSLDKIIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTESRHKLEKFRFVDFAKRKK

Nucleotide


Download         Length: 711 bp        

>NTDB_id=651262 L3474_RS08365 WP_000760673.1 1666667..1667377(+) (treR) [Streptococcus pneumoniae strain 3641/15]
ATGAAGAAATACCAACAATTATTTAAGCAAATCCAAGAAACCATTCAAAACGAGACTTACGCTGTCGGAGATTTCCTTCC
TAGCGAGCACGACCTTATGGAGCAATATCAAGTGAGTCGTGATACCGTCCGAAAGGCCCTGTCTCTCCTCCAAGAGGAAG
GATTGATCAAAAAGATAAGAGGGCAAGGTTCTCAAGTCGTCAAAGAAGAAACCGTCAATTTCCCTGTATCCAACCTAACC
AGCTACCAAGAACTAGTTAAAGAACTTGGACTGCGCTCTAAAACCAACGTGGTCAGTCTGGACAAGATTATTATTGATAA
AAAATCCTCACTGATAACCGGTTTCCCAGAGTTTCGGATGGTTTGGAAGGTGGTCCGCCAGCGTGTGGTGGATGATCTGG
TATCCGTTCTGGATACAGACTATCTGGATATGGAACTCATCCCAAATCTCACTCGCCAAATTGCTGAGCAGTCTATCTAT
TCTTATATAGAAAATGGCCTCAAACTCCTTATTGATTATGCTCAGAAGGAAATCACCATTGACCACTCAAGCGACCGAGA
CAAGATTCTCATGGACATTGGCAAAGACCCTTATGTCGTTTCGATTAAATCAAAAGTCTATCTCCAAGACGGACGCCAAT
TTCAGTTTACCGAAAGTCGCCATAAGTTAGAGAAATTTAGATTTGTAGATTTTGCAAAACGCAAGAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(89-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WVH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

59.322

100

0.593