Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   L3X15_RS04860 Genome accession   NZ_CP091423
Coordinates   988392..989771 (+) Length   459 a.a.
NCBI ID   WP_237374735.1    Uniprot ID   -
Organism   Streptococcus suis strain LSM29     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 983392..994771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3X15_RS04830 (L3X15_04830) pstA 983818..984705 (+) 888 WP_024402495.1 phosphate ABC transporter permease PstA -
  L3X15_RS04835 (L3X15_04835) pstB 984730..985533 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  L3X15_RS04840 (L3X15_04840) pstB 985545..986303 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  L3X15_RS04845 (L3X15_04845) phoU 986332..986988 (+) 657 WP_024402496.1 phosphate signaling complex protein PhoU -
  L3X15_RS04850 (L3X15_04850) - 987154..987534 (+) 381 WP_023369940.1 hypothetical protein -
  L3X15_RS04855 (L3X15_04855) ciaR 987728..988399 (+) 672 WP_009909965.1 response regulator transcription factor Regulator
  L3X15_RS04860 (L3X15_04860) ciaH 988392..989771 (+) 1380 WP_237374735.1 sensor histidine kinase Regulator
  L3X15_RS04865 (L3X15_04865) - 990102..991331 (+) 1230 WP_012027071.1 transglutaminase domain-containing protein -
  L3X15_RS04870 (L3X15_04870) tnpA 991745..992209 (+) 465 WP_237374737.1 IS200/IS605-like element ISSsu4 family transposase -
  L3X15_RS04875 (L3X15_04875) rpsT 992351..992599 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  L3X15_RS04880 (L3X15_04880) coaA 992658..993578 (-) 921 WP_012027068.1 type I pantothenate kinase -
  L3X15_RS04885 (L3X15_04885) - 993687..994277 (+) 591 WP_012027067.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51945.70 Da        Isoelectric Point: 6.8879

>NTDB_id=651060 L3X15_RS04860 WP_237374735.1 988392..989771(+) (ciaH) [Streptococcus suis strain LSM29]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVIDNGLGISDV
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=651060 L3X15_RS04860 WP_237374735.1 988392..989771(+) (ciaH) [Streptococcus suis strain LSM29]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATGTC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488