Detailed information NTG0650988

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: L3X06_RS00775
• Genome accession: NZ_CP091422
• Coordinates: 122841..123275 (+)
• Length: 144 a.a.
• NCBI ID: WP_011922561.1
• Uniprot ID: -
• Organism: Streptococcus suis strain LSM157
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117841..128275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3X06_RS00740 (L3X06_00740)	-	118590..118955 (+)	366	WP_002936568.1	DUF1033 family protein	-
L3X06_RS00745 (L3X06_00745)	-	118990..119933 (-)	944	Protein_114	S66 family peptidase	-
L3X06_RS00750 (L3X06_00750)	comYA	120019..120969 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
L3X06_RS00755 (L3X06_00755)	comYB	120881..121918 (+)	1038	WP_011921719.1	competence type IV pilus assembly protein ComGB	Machinery gene
L3X06_RS00760 (L3X06_00760)	comYC	121920..122201 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
L3X06_RS00765 (L3X06_00765)	comGD	122182..122589 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	-
L3X06_RS00770 (L3X06_00770)	comYE	122561..122854 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
L3X06_RS00775 (L3X06_00775)	comGF/cglF	122841..123275 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
L3X06_RS00780 (L3X06_00780)	comGG	123253..123663 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	-
L3X06_RS00785 (L3X06_00785)	comYH	123720..124673 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
L3X06_RS00790 (L3X06_00790)	-	124723..125910 (+)	1188	WP_012775422.1	acetate kinase	-
L3X06_RS00795 (L3X06_00795)	-	126225..126776 (+)	552	WP_012774908.1	folate family ECF transporter S component	-
L3X06_RS00800 (L3X06_00800)	-	126832..128088 (+)	1257	WP_011921729.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16491.85 Da
• Isoelectric Point: 5.9234

>NTDB_id=650988 L3X06_RS00775 WP_011922561.1 122841..123275(+) (comGF/cglF) [Streptococcus suis strain LSM157]
MLKSKIPAFTLLECLVVLVILSGSLLIFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSWSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=650988 L3X06_RS00775 WP_011922561.1 122841..123275(+) (comGF/cglF) [Streptococcus suis strain LSM157]
TTGTTAAAAAGTAAAATTCCTGCTTTTACACTCTTGGAATGTTTGGTGGTTCTAGTCATTCTGTCAGGTAGCCTCTTGAT
TTTTGAAGGCTTATCCAAATTACTAGTCCAGGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGTGAA
CAGGCTTTGGCCTTTGGCAAGTCATGGTCGGATGATTTTCGGAAAACAAATGATAGAGGCCAGGGTTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GAACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae Rx1	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae D39	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae R6	52.482	97.917	0.514
comGF/cglF	Streptococcus mitis NCTC 12261	52.985	93.056	0.493
comYF	Streptococcus mutans UA140	48.611	100	0.486
comYF	Streptococcus mutans UA159	47.917	100	0.479
comGF/cglF	Streptococcus mitis SK321	50	93.056	0.465
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.917	0.444