Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA62_RS14325 Genome accession   NZ_CP107998
Coordinates   3368651..3369316 (+) Length   221 a.a.
NCBI ID   WP_328678914.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00343     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3363651..3374316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA62_RS14295 (OHA62_14290) gcvH 3363828..3364205 (+) 378 WP_019058529.1 glycine cleavage system protein GcvH -
  OHA62_RS14300 (OHA62_14295) glyA 3364221..3365495 (+) 1275 WP_328678909.1 serine hydroxymethyltransferase -
  OHA62_RS14305 (OHA62_14300) - 3365588..3366955 (+) 1368 WP_328678910.1 L-serine ammonia-lyase -
  OHA62_RS14310 (OHA62_14305) - 3367185..3367799 (+) 615 WP_328678911.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
  OHA62_RS14315 (OHA62_14310) - 3367799..3368329 (+) 531 WP_328678912.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  OHA62_RS14320 (OHA62_14315) - 3368283..3368654 (+) 372 WP_328678913.1 hypothetical protein -
  OHA62_RS14325 (OHA62_14320) vraR 3368651..3369316 (+) 666 WP_328678914.1 response regulator transcription factor Regulator
  OHA62_RS14330 (OHA62_14325) - 3369671..3370099 (+) 429 WP_328678915.1 STAS domain-containing protein -
  OHA62_RS14335 (OHA62_14330) - 3370197..3370961 (+) 765 WP_328678916.1 ANTAR domain-containing protein -
  OHA62_RS14340 (OHA62_14335) - 3371068..3371784 (+) 717 WP_328678917.1 GAF and ANTAR domain-containing protein -
  OHA62_RS14345 (OHA62_14340) - 3371860..3372948 (-) 1089 WP_328678918.1 NUDIX domain-containing protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23483.21 Da        Isoelectric Point: 6.7667

>NTDB_id=650985 OHA62_RS14325 WP_328678914.1 3368651..3369316(+) (vraR) [Streptomyces sp. NBC_00343]
MIRVLLVDDDPLVRSGLRLMLSGADDIEVVAEAADGGEVPALVDEHAPDLVLMDIRMPGVDGLRATELLRARPGAPAVVM
LTTFKDDEQVLGALRAGAAGFLLKHTPPAEIVAAVRRVKAGEPVLSPAVTEQLIARVTQGGDTTGPRRPGTAKARIRLDR
LGDREREVAVAVGRGRANAEIAAELYMSVATVKAHVSHILTKLEHTNRVQIALTVHYAGLV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=650985 OHA62_RS14325 WP_328678914.1 3368651..3369316(+) (vraR) [Streptomyces sp. NBC_00343]
ATGATCCGTGTGCTGCTCGTCGACGACGACCCGCTGGTCCGCTCAGGACTCCGCCTCATGCTCAGCGGCGCCGACGACAT
CGAGGTCGTGGCCGAGGCGGCGGACGGCGGCGAGGTGCCCGCCCTGGTCGACGAGCACGCCCCCGACCTGGTGCTGATGG
ACATCCGGATGCCGGGCGTGGACGGCCTGAGGGCGACCGAGCTGCTGCGGGCCCGGCCCGGCGCACCGGCCGTCGTGATG
CTGACGACCTTCAAGGACGACGAGCAGGTCCTCGGTGCGCTGCGCGCGGGCGCGGCCGGTTTCCTGCTCAAGCACACCCC
GCCCGCCGAGATCGTCGCGGCGGTGCGCCGGGTGAAGGCGGGCGAACCGGTGCTCTCCCCCGCGGTGACCGAGCAGCTCA
TCGCCCGGGTCACCCAGGGCGGCGATACGACAGGCCCGCGCCGGCCGGGAACCGCCAAGGCCCGTATCCGCCTCGACCGG
CTGGGCGACCGGGAACGCGAGGTCGCCGTGGCTGTCGGCCGAGGCAGGGCCAACGCGGAGATCGCGGCCGAACTGTACAT
GAGCGTGGCCACCGTCAAGGCCCACGTCTCCCACATCCTCACCAAGCTGGAACACACCAACCGGGTCCAGATCGCCCTGA
CCGTGCACTACGCGGGGCTGGTCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-213)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.557

100

0.376